Kayesh Mohammad Enamul Hoque, Khalil Ibrahim, Kohara Michinori, Tsukiyama-Kohara Kyoko
Department of Microbiology and Public Health, Faculty of Animal Science and Veterinary Medicine, Patuakhali Science and Technology University, Barishal 8210, Bangladesh.
Department of Livestock Services, Ministry of Fisheries & Livestock, Government of the Peoples Republic of Bangladesh, Dhaka 1215, Bangladesh.
Trop Med Infect Dis. 2023 Jan 3;8(1):32. doi: 10.3390/tropicalmed8010032.
Dengue is a prevalent and rapidly spreading mosquito-borne viral disease affecting humans. The geographic range of dengue is expanding, and much like in many other tropical regions of the world, dengue has become a major public health issue in Bangladesh. Until a large epidemic dengue outbreak in 2000, sporadic outbreaks have occurred in Bangladesh since 1964. After 2000, varying intensities of dengue activity were observed each year until 2018. However, in 2019, Bangladesh experienced the largest dengue epidemic in its history, with 101,354 dengue cases and 164 dengue-related deaths. Notably, this outbreak occurred in many regions that were previously considered free of the disease. As of 10 December 2022, a total of 60,078 dengue cases and 266 dengue-related deaths were reported in Bangladesh, with the 2022 outbreak being the second largest since 2000. There is an increased genetic diversity of the dengue virus (DENV) in Bangladesh and all four DENV serotypes are prevalent and co-circulating, which increases the risk for severe dengue owing to the antibody-dependent enhancement effect. Vector control remains the mainstay of dengue outbreak prevention; however, the vector control programs adopted in Bangladesh seem inadequate, requiring improved vector control strategies. In this review, we provide an overview of the epidemiology of DENV infection and the risks for a severe dengue outbreak in Bangladesh. Additionally, we discuss different dengue vector control strategies, from which the most suitable and effective measures can be applied in the context of Bangladesh for tackling future dengue epidemics.
登革热是一种由蚊子传播的病毒性疾病，在人类中普遍存在且传播迅速。登革热的地理范围正在扩大，与世界上许多其他热带地区一样，登革热已成为孟加拉国的一个主要公共卫生问题。在2000年大规模登革热疫情爆发之前，自1964年以来孟加拉国就曾出现过零星疫情。2000年之后，直到2018年每年都观察到不同强度的登革热活动。然而，2019年，孟加拉国经历了其历史上最大规模的登革热疫情，有101354例登革热病例和164例与登革热相关的死亡病例。值得注意的是，这次疫情发生在许多以前被认为没有这种疾病的地区。截至2022年12月10日，孟加拉国共报告了60078例登革热病例和266例与登革热相关的死亡病例，2022年的疫情是2000年以来第二大规模的疫情。孟加拉国登革热病毒（DENV）的基因多样性增加，所有四种DENV血清型都普遍存在且共同传播，这由于抗体依赖性增强作用增加了严重登革热的风险。病媒控制仍然是预防登革热疫情的主要手段；然而，孟加拉国采用的病媒控制计划似乎并不充分，需要改进病媒控制策略。在本综述中，我们概述了DENV感染的流行病学以及孟加拉国发生严重登革热疫情的风险。此外，我们讨论了不同的登革热病媒控制策略，从中可以在孟加拉国的背景下应用最合适和有效的措施来应对未来的登革热疫情。
