D'Souza Arkiev, Bolsterlee Bart, Herbert Robert D
NeuRA, Randwick, NSW, Australia.
School of Medical Sciences, University of New South Wales, Randwick, NSW, Australia.
Front Bioeng Biotechnol. 2020 Jun 9;8:613. doi: 10.3389/fbioe.2020.00613. eCollection 2020.
To compare intramuscular fat fraction in people who have ankle contractures following stroke with the intramuscular fat fraction in control participants. mDixon MRI images were used to quantify intramuscular fat fractions in the medial gastrocnemius muscles of people who had experienced a hemiparetic stroke ( = 14, mean age 60 ± 13 years) and control participants ( = 18, mean age 66 ± 12 years). Intramuscular fat fractions were similar in the paretic and non-paretic sides of stroke patients (mean on paretic side 14.5%, non-paretic side 12.8%, difference 1.6%, 95% confidence interval -0.7 to 4.1%). The intramuscular fat fraction on the paretic side was higher than in the control group (mean intramuscular fat fraction in control muscles 7.6%; difference 7.8%, 95% confidence interval 4.6-10.9%). The difference between intramuscular fat fractions in non-paretic and control legs increased with age. Body mass index was similar in stroke patients and controls. There was no association between medial gastrocnemius intramuscular fat fraction and dorsiflexion range. Muscles of stroke patients had elevated intramuscular fat fractions compared to muscles from control participants which were not explained by differences in body mass index. There is no clear relationship between intramuscular fat in the medial gastrocnemius muscle and dorsiflexion range of motion.
比较中风后出现踝关节挛缩的人群与对照参与者的肌肉内脂肪分数。使用mDixon MRI图像对偏瘫性中风患者（n = 14，平均年龄60±13岁）和对照参与者（n = 18，平均年龄66±12岁）腓肠肌内侧的肌肉内脂肪分数进行量化。中风患者患侧和未患侧的肌肉内脂肪分数相似（患侧平均为14.5%，未患侧为12.8%，差异为1.6%，95%置信区间为-0.7至4.1%）。患侧的肌肉内脂肪分数高于对照组（对照肌肉的平均肌肉内脂肪分数为7.6%；差异为7.8%，95%置信区间为4.6 - 10.9%）。未患侧与对照侧腿部肌肉内脂肪分数的差异随年龄增加。中风患者和对照组的体重指数相似。腓肠肌内侧肌肉内脂肪分数与背屈范围之间无关联。与对照参与者的肌肉相比，中风患者的肌肉内脂肪分数升高，这无法用体重指数的差异来解释。腓肠肌内侧的肌肉内脂肪与背屈活动范围之间没有明确的关系。
