使用单光子发射计算机断层扫描（SPECT）进行¹³¹I放射免疫治疗的定量分析。
Quantitation in 131I-radioimmunotherapy using SPECT.
作者信息
Riggs S J, Green A J, Begent R H, Bagshawe K D
机构信息
Department of Medical Oncology, Charing Cross and Westminster Medical School, Charing Cross Hospital, London, UK.
出版信息
Int J Cancer Suppl. 1988;2:95-8.
Quantitation from planar imaging and single photon emission computed tomography (SPECT) were compared in phantom studies and in patients receiving therapeutic doses of 131I-labelled anti-CEA. During the reconstruction of the data for SPECT quantitation attenuation correction and a correction for Compton scatter were used. The limitations of both methods were examined using the phantom studies and it was shown that practical SPECT quantitation could be achieved in patients given therapeutic doses of 131I-labelled anti-CEA, and furthermore, that SPECT appeared to give a more accurate estimate of the activity concentration.
在体模研究以及接受治疗剂量¹³¹I标记抗癌胚抗原（CEA）的患者中，对平面显像和单光子发射计算机断层扫描（SPECT）的定量分析进行了比较。在SPECT定量分析的数据重建过程中，使用了衰减校正和康普顿散射校正。通过体模研究检验了两种方法的局限性，结果表明，在给予治疗剂量¹³¹I标记抗CEA的患者中可以实现实用的SPECT定量分析，而且，SPECT似乎能更准确地估计活度浓度。
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