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单孔腹腔镜胆囊切除术适应证和结局的时间变化:一项韩国多中心研究。

The chronological change of indications and outcomes for single-incision laparoscopic cholecystectomy: a Korean multicenter study.

机构信息

Division of Hepatobiliary Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Surgery, Dong-A University Hospital, Dong-A University, College of Medicine, Busan, Republic of Korea.

出版信息

Surg Endosc. 2021 Jun;35(6):3025-3032. doi: 10.1007/s00464-020-07748-5. Epub 2020 Jun 24.

Abstract

BACKGROUND

Although single-incision laparoscopic cholecystectomy (SILC) is a common procedure, the change in its surgical indications and perioperative outcomes has not been analyzed.

METHODS

We collected the clinical data of patients who underwent pure SILC in 9 centers between 2009 and 2018 and compared the perioperative outcomes.

RESULTS

In this period, 6497 patients underwent SILC. Of these, 2583 were for gallbladder (GB) stone (39.7%), 774 were for GB polyp (11.9%), 994 were for chronic cholecystitis (15.3%), and 1492 were for acute cholecystitis (AC) (23%). 162 patients (2.5%) experienced complication, including 20 patients (0.2%) suffering from biliary leakage. The number of patients who underwent SILC for AC increased over time (p = 0.028), leading to an accumulation of experience (27.4 vs 23.7%, p = 0.002). The patients in late period were more likely to have undergone a previous laparotomy (29.5 vs 20.2%, p = 0.006), and to have a shorter operation time (47.0 vs 58.8 min, p < 0.001). Male (odds ratio [OR]; 1.673, 95% confidence interval [CI] 1.090-2.569, p = 0.019) and moderate or severe acute cholecystitis (OR; 2.602, 95% CI 1.677-4.037, p < 0.001) were independent predictive factors for gallbladder perforation during surgery, and open conversion (OR; 5.793, 95% CI 3.130-10.721, p < 0.001) and pathologically proven acute cholecystitis or empyema (OR; 4.107, 95% CI 2.461-6.854, p < 0.001) were related with intraoperative gallbladder perforation CONCLUSION: SILC has expanded indication in late period. In this period, the patients had shorter operation times and a similar rate of severe complications, despite there being more numerous patients with AC.

摘要

背景

虽然单切口腹腔镜胆囊切除术(SILC)是一种常见的手术,但它的手术适应证和围手术期结果的变化尚未被分析。

方法

我们收集了 9 家中心在 2009 年至 2018 年间接受纯 SILC 的患者的临床资料,并比较了围手术期结果。

结果

在此期间,有 6497 例患者接受了 SILC。其中,胆囊(GB)结石 2583 例(39.7%),胆囊息肉 774 例(11.9%),慢性胆囊炎 994 例(15.3%),急性胆囊炎(AC)1492 例(23%)。162 例(2.5%)患者发生并发症,包括 20 例(0.2%)胆漏。接受 SILC 治疗 AC 的患者人数随时间增加(p=0.028),导致经验积累(27.4%比 23.7%,p=0.002)。后期患者更有可能接受过剖腹手术(29.5%比 20.2%,p=0.006),手术时间更短(47.0 分钟比 58.8 分钟,p<0.001)。男性(比值比[OR];1.673,95%置信区间[CI]1.090-2.569,p=0.019)和中重度急性胆囊炎(OR;2.602,95%CI 1.677-4.037,p<0.001)是术中胆囊穿孔的独立预测因素,中转开腹(OR;5.793,95%CI 3.130-10.721,p<0.001)和病理证实的急性胆囊炎或积脓(OR;4.107,95%CI 2.461-6.854,p<0.001)与术中胆囊穿孔有关。

结论

SILC 的适应证在后期有所扩大。在此期间,尽管 AC 患者数量更多,但患者的手术时间更短,严重并发症的发生率相似。

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