Department of Biomedical, Surgical and Dental Sciences, University of Milano, Milan, Italy.
IRCCS Orthopedic Institute Galeazzi, Milano, Italy.
Oral Dis. 2020 Nov;26(8):1803-1809. doi: 10.1111/odi.13505. Epub 2020 Jul 13.
Ectodermal dysplasia syndrome is a complex group of genetic disorders identified by the abnormal development of the ectodermal structures. The aim of this retrospective clinical case series report was to evaluate the outcomes of the ectodermal dysplasia syndrome patients that underwent zygomatic implant surgery.
A total of 9 ectodermal dysplasia syndrome patients aged between 21 and 56 years (mean age 36.8) with severely atrophic maxilla were included in this study. All the patients were treated with a total of 19 zygomatic implants. The mean follow-up of the patients was 55 months (with a range of 44-84 months). The implant survival rate was evaluated as a primary outcome. The intra- and postoperative complications were evaluated as additional criteria for success.
The overall implant survival rate was 100% without any complications. Final or provisional prosthesis was delivered on the same day of surgery, which resulted in an improvement of the quality of life of the patients.
According to the results of this study, zygomatic surgery can be considered as a viable and safe alternative to conventional treatment modalities for oral rehabilitation of ectodermal dysplasia syndrome patients.
外胚层发育不良综合征是一组由外胚层结构异常发育引起的复杂遗传疾病。本回顾性临床病例系列报告的目的是评估接受颧骨种植手术的外胚层发育不良综合征患者的治疗结果。
本研究共纳入 9 名年龄在 21 至 56 岁(平均年龄 36.8 岁)、上颌骨严重萎缩的外胚层发育不良综合征患者。所有患者均接受了总共 19 枚颧骨种植体治疗。患者的平均随访时间为 55 个月(44-84 个月)。种植体存活率被评估为主要结果。术中及术后并发症被评估为成功的附加标准。
所有患者的种植体总存活率为 100%,无任何并发症。手术当天就为患者佩戴了最终或临时修复体,这提高了患者的生活质量。
根据本研究结果,颧骨手术可以被认为是外胚层发育不良综合征患者口腔修复的一种可行且安全的替代传统治疗方法。