Department of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.
Org Lett. 2020 Jul 17;22(14):5502-5505. doi: 10.1021/acs.orglett.0c01854. Epub 2020 Jun 25.
This research successfully achieved a Cu(II)-catalyzed 6π-photocyclization of non-6π substrates. The photoenolization converts -alkylphenyl alkynl ketones into a triene-type intermediate which undergoes the subsequent 6π-photocyclization to give naphthol as the final product. Cu(II) catalyst facilitates both photoenolization and 6π-photocyclization. This research highlighted the tandem reaction strategy and the importance of metal catalysis in photochemistry.
本研究成功实现了非 6π 底物的 Cu(II)催化 6π-光环化反应。光烯醇化将 -烷基苯基炔基酮转化为三烯型中间体，随后进行后续的 6π-光环化反应，得到萘酚作为最终产物。Cu(II)催化剂促进了光烯醇化和 6π-光环化反应。本研究强调了串联反应策略和金属催化在光化学中的重要性。
