Andersen Mathilde Borring, Lund Marie Louise, Jacobsen Søren, Kümler Thomas, Simonsen Stine, Ravn Pernille
Ugeskr Laeger. 2020 Jun 22;182(26).
This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.
这是一份关于新冠肺炎非典型表现的报告。尽管胸部CT显示有典型的新冠肺炎病变,但该患者肺部症状轻微,且在住院几天后出现了严重的肢端缺血性改变。这种情况无法用伴有低血压和低灌注的经典脓毒症、弥散性血管内凝血、血管炎、心内膜炎或严重外周动脉硬化来解释。皮肤活检显示有微血栓形成,被解释为与新冠肺炎相关的凝血系统激活。显然,新冠肺炎存在多种表型。