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中国武汉老年人中 COVID-19 的流行病学。

Epidemiology of COVID-19 in older persons, Wuhan, China.

机构信息

Wuhan Centers for Disease Prevention and Control, Wuhan, China.

Department of Gastrointestinal, Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Age Ageing. 2020 Aug 24;49(5):706-712. doi: 10.1093/ageing/afaa145.

DOI:10.1093/ageing/afaa145
PMID:32584953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7337701/
Abstract

BACKGROUND

the epidemiological characteristics of older patients with COVID-19 was far from clear.

OBJECTIVE

to explore the epidemiology of older patients with COVID-19 in Wuhan, China.

DESIGN

a retrospective cross-sectional study.

SETTING

a population-based study.

SUBJECTS

the resident older patients (>65 years) diagnosed with COVID-19.

METHODS

city-wide case series reported to Wuhan Center for Disease Control and Prevention from 12 December 2019 to 17 March 2020 were included. The epidemic curves were constructed by dates of disease onset.

RESULTS

14,238 confirmed COVID-19 cases were older persons. The number of male cases were slightly less than female cases (1:1.01). The attack rate of COVID-19 in the older persons was 11.49‰ in Wuhan. There was a rapid increase of disease at the early stage of the epidemic and then a gradual and steady decrease was performed. 3,723 (26.15%) and 734 (5.16%) patients were diagnosed as severe and critical cases, respectively. The attributable crude fatality ratio of COVID-19 in the older population was 222.57/100,000, and the crude fatality ratio of COVID was 19.37%. The proportion of severe and critical cases, and fatality ratio were both higher in downtown area and increased with age.

CONCLUSIONS

the older persons are sensitive to COVID-19. The proportion of severe and critical cases and fatality ratio are higher than that in children and younger adults. Strengthen the protection and control strategies for the older adults are of priorities. More detailed epidemiological and clinical information should be measured in further studies.

摘要

背景

COVID-19 老年患者的流行病学特征尚不清楚。

目的

探讨中国武汉 COVID-19 老年患者的流行病学特征。

设计

回顾性横断面研究。

设置

基于人群的研究。

对象

诊断为 COVID-19 的老年居民(>65 岁)。

方法

纳入 2019 年 12 月 12 日至 2020 年 3 月 17 日向武汉疾病预防控制中心报告的全市病例系列。通过发病日期构建流行曲线。

结果

14238 例确诊 COVID-19 患者为老年人。男性病例略少于女性病例(1:1.01)。COVID-19 在老年人中的发病率为 11.49‰。疫情早期病例迅速增加,然后逐渐稳定下降。3723 例(26.15%)和 734 例(5.16%)患者被诊断为重症和危重症病例。COVID-19 在老年人群中的归因粗死亡率为 222.57/100,000,COVID 的粗死亡率为 19.37%。重症和危重症病例的比例以及死亡率在市中心地区均较高,并随年龄增长而增加。

结论

老年人对 COVID-19 敏感。重症和危重症病例的比例以及死亡率均高于儿童和年轻成年人。加强对老年人的保护和控制策略是重中之重。在进一步的研究中应测量更详细的流行病学和临床信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bf/7444664/443fb67baf98/AGEING_49_5_706_f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bf/7444664/443fb67baf98/AGEING_49_5_706_f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bf/7444664/443fb67baf98/AGEING_49_5_706_f1.jpg

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