Papageorgiou C, Stampf J L, Benezra C
Laboratoire de Dermatochimie, Associé au CNRS, Université Louis Pasteur, Strasbourg, France.
Arch Dermatol Res. 1988;280(1):5-7. doi: 10.1007/BF00412680.
Allergic contact dermatitis (ACD), an immunological reaction of the skin resulting from contact with reactive compounds occurring in plants was shown to the enantiospecific (animals sensitized to a compound do not react to its nonsuperimposable mirror image). Thus, when guinea pigs were experimentally sensitized to (+)-tulipalin B (a compound present in tulip bulbs) they did not react to its enantiomer, (-)-tulipalin B. This was also true for (+)- and (-)-beta-hydroxy-gamma-methyl-alpha-methylene-gamma-butyrolactones.
过敏性接触性皮炎（ACD）是一种皮肤免疫反应，由接触植物中存在的反应性化合物引起，已被证明具有对映体特异性（对一种化合物致敏的动物不会对其不可重叠的镜像产生反应）。因此，当豚鼠经实验对（+）-郁金香素B（郁金香球茎中存在的一种化合物）致敏时，它们对其对映体（-）-郁金香素B没有反应。对于（+）-和（-）-β-羟基-γ-甲基-α-亚甲基-γ-丁内酯也是如此。
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