治疗老年糖尿病患者动脉粥样硬化性心血管疾病一级预防中的血脂异常

Treating Dyslipidemias in the Primary Prevention of Atherosclerotic Cardiovascular Disease in Older Adults with Diabetes Mellitus.

作者信息

Tan MengHee, MacEachern Mark Paul

机构信息

Division of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48105, USA.

Taubman Health Sciences Library, University of Michigan, 1135 Catherine Street, Ann Arbor, MI 48109, USA.

出版信息

Clin Geriatr Med. 2020 Aug;36(3):457-476. doi: 10.1016/j.cger.2020.04.006. Epub 2020 Apr 17.

DOI:10.1016/j.cger.2020.04.006

PMID:32586475

Abstract

People with diabetes mellitus (DM), especially those who are older, are at higher risk for premature morbidity and mortality related to atherosclerotic cardiovascular disease (ASCVD). Clinical practice guidelines recommend statin therapy for people with DM ages 40 to 75 years. The evidence for those greater than 75 years of age is relatively limited at present. Other health problems should be considered when planning ASCVD primary prevention in adults ages greater than 75 years with DM. Clinicians should discuss the risks and benefits of each plan with these patients and their caregivers.

摘要

糖尿病患者，尤其是老年患者，发生与动脉粥样硬化性心血管疾病（ASCVD）相关的过早发病和死亡的风险更高。临床实践指南建议40至75岁的糖尿病患者接受他汀类药物治疗。目前，75岁以上患者的相关证据相对有限。在为75岁以上患有糖尿病的成年人制定ASCVD一级预防计划时，应考虑其他健康问题。临床医生应与这些患者及其护理人员讨论每个治疗方案的风险和益处。