Section of Endocrinology, Diabetes, and Metabolism, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
Section of Endocrinology, Diabetes, and Metabolism, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.
Clin Geriatr Med. 2020 Aug;36(3):527-547. doi: 10.1016/j.cger.2020.04.010. Epub 2020 Apr 17.
Nonalcoholic fatty liver disease (NAFLD) is common in older patients with type 2 diabetes. In older patients with type 2 diabetes, the presence of NAFLD is associated with a higher risk of hepatic (eg, nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma) and extrahepatic (eg, cardiovascular disease, sarcopenia, and dementia) complications than that observed in other patient groups. For this reason, appropriate identification and management of NAFLD are clinically relevant particularly in the group of older patients with type 2 diabetes. In this regard, clinicians should consider the peculiar characteristics of elderly patients, such as frailty, multimorbidity, and polypharmacy.
非酒精性脂肪性肝病（NAFLD）在 2 型糖尿病老年患者中较为常见。在 2 型糖尿病老年患者中，与其他患者群体相比，NAFLD 的存在与更高的肝脏（如非酒精性脂肪性肝炎、肝硬化和肝细胞癌）和肝外（如心血管疾病、肌肉减少症和痴呆）并发症风险相关。出于这个原因，NAFLD 的适当识别和管理在 2 型糖尿病老年患者群体中具有重要的临床意义。在这方面，临床医生应考虑老年患者的特殊特征，如虚弱、多种合并症和多种药物治疗。
