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枕骨大孔脑膜瘤

Foramen magnum meningiomas.

作者信息

Bir Shyamal C, Maiti Tanmoy K, Nanda Anil

机构信息

Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, LA, United States.

Department of Neurosurgery, Rutgers-New Jersey Medical School, Newark, NJ, United States.

出版信息

Handb Clin Neurol. 2020;170:167-174. doi: 10.1016/B978-0-12-822198-3.00038-0.

Abstract

The foramen magnum meningioma (FMM) is one of most challenging tumors among all the meningiomas because of its distinctive location, clinical course, insidious onset, and the relative large size of the tumor during presentation. These tumors are slow-growing and clinical symptoms vary according to involvement of different structures including the spinal cord, vertebral artery, lower cranial nerves, and medulla oblongata. Controversies regarding appropriate surgical approach for resection of tumor in this unique location continue. Tumors in the posterior or posterolateral region of the foramen magnum is accessible by midline suboccipital approach. The anterior and anterolateral tumors are encountered by various modifications of the far lateral approach. Drilling of condylar fossa is adequate in most of the cases as tumors often create a surgical corridor. However, an anterior tumor with significant extension on both sides of midline may require variable amounts of condyle resection. Here we review the FMMs with an emphasis on surgical approaches.

摘要

枕骨大孔脑膜瘤(FMM)是所有脑膜瘤中最具挑战性的肿瘤之一,因其位置独特、临床病程、起病隐匿,且在就诊时肿瘤相对较大。这些肿瘤生长缓慢,临床症状因不同结构受累而有所不同,包括脊髓、椎动脉、下颅神经和延髓。对于在这个独特位置切除肿瘤的合适手术方法仍存在争议。枕骨大孔后或后外侧区域的肿瘤可通过枕下中线入路进行手术。前侧和前外侧肿瘤则需要通过各种改良的远外侧入路来处理。在大多数情况下,磨除髁窝就足够了,因为肿瘤常常会形成一个手术通道。然而,中线两侧有明显延伸的前侧肿瘤可能需要不同程度的髁突切除。在此,我们重点回顾枕骨大孔脑膜瘤的手术入路。

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