Nicholas N S
Queen Charlotte's Hospital, London.
Br J Hosp Med. 1988 Jan;39(1):50-3.
The effects of pregnancy on the clinical course of the rheumatic diseases is not only variable but often unpredictable. Disease activity at the onset of pregnancy will have great bearing on fetal outcome. Thus the use of potentially harmful drug combinations in pregnancy has to be weighed against theoretical teratogenic effects. This review outlines some of these dilemmas.
妊娠对风湿性疾病临床病程的影响不仅多变,而且往往不可预测。妊娠开始时的疾病活动度对胎儿结局有很大影响。因此,必须权衡孕期使用潜在有害药物组合与理论上的致畸作用。本综述概述了其中一些困境。