Department of Laboratory Medicine (Microbiology), Hospital AZ Damiaan, Ostend, Belgium.
Department of Endocrinology, Hospital AZ Damiaan, Ostend, Belgium.
Acta Clin Belg. 2022 Feb;77(1):137-141. doi: 10.1080/17843286.2020.1787635. Epub 2020 Jun 26.
Syphilis is a systemic, infectious disease caused by and is notorious for the variety of its clinical presentations.
We report a case of secondary syphilis with thyroid gland and ocular involvement in a human immunodeficiency virus (HIV) negative patient.
We present the patient's history, clinical findings, laboratory test results, imaging and management.
A 39-year-old Caucasian, HIV unaffected woman presented with acute midline neck swelling, dyspnea and difficulty to talk or swallow. Serologic tests for syphilis were positive. PCR performed on a thyroid fine needle aspiration cytology (FNAC) aspirate was positive for . Skin lesions and unilateral loss of vision were present. Treatment with intravenous benzyl-penicillin showed a good regression of symptoms.
We report an unusual case of thyroid swelling in a secondary syphilis infection. Awareness of syphilis as a differential diagnosis is important in a risk population.
梅毒是一种由 引起的系统性传染病，其临床表现多种多样，声名狼藉。
我们报告一例 HIV 阴性患者发生的伴有甲状腺和眼部受累的二期梅毒。
我们介绍了患者的病史、临床发现、实验室检查结果、影像学表现和治疗方法。
一名 39 岁的白人、未感染 HIV 的女性患者出现急性中线颈部肿胀、呼吸困难以及难以说话或吞咽。梅毒血清学检查阳性。甲状腺细针抽吸细胞学（FNAC）标本的 PCR 检测结果为阳性。存在皮肤损伤和单侧视力丧失。静脉注射苄星青霉素治疗后症状明显缓解。
我们报告了一例在二期梅毒感染中出现甲状腺肿胀的不常见病例。在高危人群中，认识到梅毒是一种鉴别诊断非常重要。
