Nazareth Alexander, Bains Sukhraj S, Andras Lindsay M, Goldstein Rachel Y, Kay Robert M
Keck School of Medicine, University of Southern California.
Children's Orthopaedic Center, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Medicine (Baltimore). 2020 Jun 26;99(26):e20517. doi: 10.1097/MD.0000000000020517.
Literature regarding the value of pre-operative nasal methicillin resistant Staphylococcus aureus (MRSA) swabs to predict surgical site infections (SSIs) in children undergoing lower extremity surgery is limited. The purpose of our study was to determine if pre-operative nasal MRSA swab results were predictive of SSI development in children undergoing a femoral varus derotational osteotomy (VDRO).Patients who underwent VDRO between 2004-2016 were reviewed to determine pre-operative MRSA colonization rates and SSI devolvement rates. Patients with less than 1 year of follow-up, previous history of infections, or absent pre-operative MRSA swab were excluded. SSI rates of patients with negative MRSA and positive MRSA swab result were compared using the Fisher exact test. Aside from contact isolation precautions, no other changes in treatment were made during inpatient hospital course based on positive pre-operative nasal MRSA swab results.247 patients met the inclusion criteria (mean age: 9.3 ± 3.6 years, 62% male). There were 242 (98%) patients with a negative MRSA swab and 5 (2%) patients with a positive MRSA swab. Out of the 242 patients with a negative MRSA swab, 4 developed an SSI. Of the patients with positive MRSA swab results, 0% (0/5) developed an SSI compared to 1.7% (4/242) of negative MRSA swab results who developed an SSI. Results indicated no significant difference in SSI development rates between the groups (P = 1.00).In this series of children undergoing VDRO surgery, the results of a pre-operative MRSA nasal swab had no relationship to SSI incidence and no impact on clinical patient care. Pre-operative MRSA nasal swabs appear to be of limited benefit for routine pre-operative screening in this patient population.Level III, retrospective comparative.
关于术前鼻腔耐甲氧西林金黄色葡萄球菌(MRSA)拭子对预测接受下肢手术儿童手术部位感染(SSI)价值的文献有限。我们研究的目的是确定术前鼻腔MRSA拭子结果是否能预测接受股骨内翻旋转截骨术(VDRO)儿童的SSI发生情况。
回顾了2004年至2016年期间接受VDRO的患者,以确定术前MRSA定植率和SSI发生率。随访时间少于1年、有既往感染史或术前未进行MRSA拭子检测的患者被排除。使用Fisher精确检验比较MRSA拭子结果为阴性和阳性患者的SSI发生率。除接触隔离预防措施外,住院期间未根据术前鼻腔MRSA拭子结果阳性对治疗进行其他改变。
247例患者符合纳入标准(平均年龄:9.3±3.6岁,62%为男性)。MRSA拭子结果为阴性的患者有242例(98%),阳性的患者有5例(2%)。在242例MRSA拭子结果为阴性的患者中,4例发生了SSI。MRSA拭子结果为阳性的患者中,SSI发生率为0%(0/5),而MRSA拭子结果为阴性的患者中SSI发生率为1.7%(4/242)。结果表明两组间SSI发生率无显著差异(P = 1.00)。
在这组接受VDRO手术的儿童中,术前MRSA鼻腔拭子结果与SSI发生率无关,对临床患者护理也无影响。术前MRSA鼻腔拭子对该患者群体的常规术前筛查似乎益处有限。三级,回顾性比较研究。