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巴西南部社区居住老年人的体重指数与死亡率

Body mass index and mortality among community-dwelling elderly of Southern Brazil.

作者信息

Cardoso Andressa Souza, Xavier Mariana Otero, Dos Santos Costa Caroline, Tomasi Elaine, Cesar Juraci Almeida, Gonzalez Maria Cristina, Domingues Marlos Rodrigues, Barbosa-Silva Thiago Gonzalez, Bielemann Renata Moraes

机构信息

School of Nutrition, Federal University of Pelotas, Brazil.

Post-Graduate Program in Epidemiology, Federal University of Pelotas, Brazil.

出版信息

Prev Med. 2020 Oct;139:106173. doi: 10.1016/j.ypmed.2020.106173. Epub 2020 Jun 24.

Abstract

This study aims to measure the association between body mass index (BMI), comparing two different classifications, and mortality among community-dwelling elderly considering myopenia in Pelotas, Brazil. This is a longitudinal study started in 2014, we followed 1451 elderly people (≥ 60 years) enrolled in the "COMO VAI?" study. BMI was classified according to the World Health Organization (WHO) and the classification with specific cutoff points for older adults. Myopenia was measured by calf circumference (≤33 cm for women and ≤34 cm for men). Cox proportional-hazards models were used to test associations controlling for sociodemographic and behavioral characteristics and number of morbidities. Nearly 10% (N = 145) of the elderly died during almost three years of follow-up. We observed a L-shaped relation between BMI and mortality. Elderly with underweight had a higher mortality risk compared to those with adequate BMI in both classifications. According to the WHO classification, overweight elderly presented protection for mortality (HR: 0.58; 95% CI 0.38-0.87) when compared to those with adequate BMI. Among elderly with myopenia, overweight by WHO continued to protect against mortality, although not significantly, while those with the specific classification underweight presented a higher risk of death compared to those with normal weight (HR: 2.09; 95% CI 1.06-4.14). In conclusion the underweight increased the risk of death in community-dwelling elderly people during a follow-up of three years. The specific classification seemed to be more adequate to indicate risk of mortality in this population. Higher BMI protect against mortality when muscle mass was not considered.

摘要

本研究旨在衡量巴西佩洛塔斯地区社区居住老年人中,比较两种不同分类的体重指数(BMI)与死亡率之间的关联,并考虑肌肉减少症。这是一项始于2014年的纵向研究,我们跟踪了1451名(≥60岁)参与“情况如何?”研究的老年人。BMI根据世界卫生组织(WHO)的标准以及针对老年人的特定切点分类进行划分。肌肉减少症通过小腿围度来衡量(女性≤33厘米,男性≤34厘米)。使用Cox比例风险模型来检验控制社会人口统计学和行为特征以及发病数量后的关联。在近三年的随访期间,近10%(N = 145)的老年人死亡。我们观察到BMI与死亡率之间呈L形关系。在两种分类中,体重过轻的老年人相比BMI正常的老年人有更高的死亡风险。根据WHO分类,超重老年人与BMI正常者相比,对死亡率有保护作用(HR:0.58;95%CI 0.38 - 0.87)。在患有肌肉减少症的老年人中,按照WHO标准超重者尽管保护作用不显著,但仍继续对死亡率有保护作用,而按照特定分类体重过轻的老年人相比体重正常者有更高的死亡风险(HR:2.09;95%CI 1.06 - 4.14)。总之,体重过轻增加了社区居住老年人在三年随访期间的死亡风险。特定分类似乎更适合表明该人群的死亡风险。在不考虑肌肉量时,较高的BMI对死亡率有保护作用。

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