Kaiser W, Schmidt G A
Z Gesamte Inn Med. 1977 Mar 1;32(5):113-8.
During pregnancy the maternal calcium metabolism is submitted to special loads. Overchallenging of the functional capacity of the parathyroid gland may evoke an insufficiency of the parathyroid gland which on its part induces a fetal secondary hyperparathyroidism. Therefore, the early diagnostic recognition of the insufficiency of the parathyroid gland is of importance, since (also in basic diseases known before pregnancy) now special therapeutic conditions are given. Maternal hyperparathyroidism leads to fetal hypoprarthyroidism with resulting developmental disturbances; it furthers the tendency to abortions and perinatal mortality. Epidemiological prospective investigations have shown that among the identified cases of oligo- or asymptomatic functional disturbances of the parathyroid glands there are very often women at an age, when they are capable of bearing children. This statement confirms the postule regularly to control serum calcium content during pregnancy. Objectifying the disturbed integrity of the calcium metabolism, therapeutic measures are necessary, the details of which are demonstrated according to own experiences. In such cases the cooperation between the gynaecologist being in charge of the pregnant woman and the internist working in the field of endocrinology is to be wished.
在怀孕期间，母体的钙代谢会承受特殊负荷。甲状旁腺功能能力的过度挑战可能引发甲状旁腺功能不全，进而导致胎儿继发性甲状旁腺功能亢进。因此，早期诊断甲状旁腺功能不全很重要，因为（即使在怀孕前就已知的基础疾病中）现在有了特殊的治疗条件。母体甲状旁腺功能亢进会导致胎儿甲状旁腺功能减退，从而引发发育障碍；它还会增加流产和围产期死亡率的倾向。流行病学前瞻性研究表明，在已确诊的甲状旁腺功能轻度或无症状性紊乱病例中，很多是处于生育年龄的女性。这一说法证实了孕期定期检测血清钙含量的必要性。为了明确钙代谢紊乱的情况，需要采取治疗措施，本文将根据自身经验阐述其细节。在这种情况下，负责孕妇的妇科医生与内分泌领域的内科医生之间的合作是很有必要的。
