İnanç Leman, Sevinç Ergün, Semiz Ümit Başar
Turk Psikiyatri Derg. 2019 Winter;30(4):225-235.
The aim of this study was to compare schizophrenia patients with and without Deficit Syndrome (DS) with respect to alexithymia, depression and negative symptoms and to investigate the relationship between these variables.
A total of 210 schizophrenia patients who joined the study were grouped on the basis of the Schedule for the Deficit Syndrome (SDS). Each patient was evaluated using the Positive and Negative Syndrome Scale (PANSS), the Calgary Depression Scale for Schizophrenia (CDSS), the Toronto Alexithymia Scale (TAS) and the UKU - Side Effect Rating Scale (UKU-SERS).
The DS group had higher alexithymia scores that were not related to the negative symptoms. The prevalence of depression was significantly lower in the same group. Positive symptoms in the DS group were negatively correlated with the two TAS subscales of difficulty describing and identifying feelings. The negative symptoms scores of all the patients with and without DS correlated positively with the mean score on the TAS subscales. The severity of depressive and the negative symptoms predicted alexithymic symptoms.
Lack of a correlation between the negative symptoms and alexithymic symptoms in DS suggested that the respective symptoms represented different independent phenomena in schizophrenia. A future study might explore the relationship between alexithymia and negative symptoms in association with cognitive functioning.
本研究旨在比较伴有和不伴有缺陷综合征（DS）的精神分裂症患者在述情障碍、抑郁和阴性症状方面的差异，并探究这些变量之间的关系。
共有210名参与本研究的精神分裂症患者根据缺陷综合征评定量表（SDS）进行分组。使用阳性与阴性症状量表（PANSS）、精神分裂症卡尔加里抑郁量表（CDSS）、多伦多述情障碍量表（TAS）和UKU副反应量表（UKU-SERS）对每位患者进行评估。
DS组的述情障碍得分较高，且与阴性症状无关。该组的抑郁患病率显著较低。DS组的阳性症状与TAS描述和识别情感困难的两个分量表呈负相关。所有伴有和不伴有DS的患者的阴性症状得分均与TAS分量表的平均分呈正相关。抑郁和阴性症状的严重程度可预测述情障碍症状。
DS患者的阴性症状与述情障碍症状之间缺乏相关性，这表明在精神分裂症中，各自的症状代表了不同的独立现象。未来的研究可能会探索述情障碍与阴性症状之间与认知功能相关的关系。
