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蛛网膜囊肿致认知障碍和轻躁狂症状 1 例报告

A Case of Arachnoid Cyst Presenting with Cognitive Impairment and Hypomania Symptoms.

出版信息

Turk Psikiyatri Derg. 2020 Summer;31(2):131-136. doi: 10.5080/u23937.

Abstract

Arachnoid cysts are benign congenital malformations of the arachnoid which account for approximately 1.4% of the intracranial lesions. Although it is usually asymptomatic, it may be accompanied by headache, hydrocephalus and seizure. Psychiatric disorders associated with arachnoid cysts are rare. In this article, we present a giant arachnoid cyst with hypomania symptoms and marked cognitive impairment. A 44-year-old female patient was admitted to our outpatient clinic with a 4-year history of headache, nervousness and attention problems. Magnetic resonance imaging revealed a giant arachnoid cyst with a size of 5.5x10.5x12.5 cm was found in the left hemisphere of the patient. Considering the patient's irritability, increase in the amount of speech, flight of ideas, sleep disturbance and attention disorders, the diagnosis of hypomania was made. The neuropsychological tests showed that the speed of information processing, mental flexibility and attention functions decreased, and executive functions were impaired. The patient was consulted to the neurosurgery department. But no surgical treatment was offered. Drug therapy for hypomanic symptoms and cognitive impairment was planned, but could not be started since the patient did not attend to the follow-up exams. Albeit the lack of followup constitutes a limitation for our report, we believe that the size of the cyst, significant impairment of cognitive functions and the presence of hypomania symptoms might contribute significantly to the literature. Other cases with arachnoid cyst displaying cognitive impairment were summarized in our article.

摘要

蛛网膜囊肿是蛛网膜的良性先天性畸形,约占颅内病变的 1.4%。虽然它通常是无症状的,但可能伴有头痛、脑积水和癫痫发作。与蛛网膜囊肿相关的精神障碍很少见。本文报道了 1 例伴有轻躁狂症状和明显认知障碍的巨大蛛网膜囊肿。1 例 44 岁女性患者,头痛 4 年,伴紧张和注意力问题,来我院门诊就诊。磁共振成像显示患者左侧大脑半球有 1 个 5.5x10.5x12.5cm 的巨大蛛网膜囊肿。考虑到患者易激惹、言语量增加、思维奔逸、睡眠障碍和注意力障碍,诊断为轻躁狂。神经心理学测试显示信息处理速度、思维灵活性和注意力功能下降,执行功能受损。患者咨询神经外科,但未接受手术治疗。计划对轻躁狂症状和认知障碍进行药物治疗,但由于患者未参加随访检查,无法开始治疗。尽管缺乏随访是我们报告的一个局限性,但我们认为囊肿的大小、认知功能的显著损害以及轻躁狂症状的存在可能对文献有重要意义。我们的文章还总结了其他伴有认知障碍的蛛网膜囊肿病例。

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