Pharmacy Unit, IRCCS San Raffaele Hospital, Milan, Italy.
School of Hospital Pharmacy, University of Milan, Milan, Italy.
J Oncol Pharm Pract. 2020 Oct;26(7):1715-1720. doi: 10.1177/1078155220937389. Epub 2020 Jun 28.
The use of continuous-infusion in outpatient setting could be widely used in oncology and haematology care. Many times the lack of data stability about single drug or admixture of drugs, together with patient education and safety, make difficult the transition from inpatient to outpatient setting. Nowadays, this is a big challenge for hospital pharmacists, who must take into consideration the critical issues related to chemical and physical stability, besides microbiological one, in order to ensure high quality preparations and guarantee the safety and quality of care, to protect patients and their health. The aim of this article is to highlight the critical issues concerning the transition from inpatient to outpatient setting, with particular interest regarding chemotherapy protocols, which require preparation with long-term continuous-infusion.
连续输注在门诊中的应用可以广泛应用于肿瘤学和血液学的护理。由于缺乏关于单一药物或药物混合物的数据稳定性,以及患者的教育和安全问题,使得从住院环境过渡到门诊环境变得困难。如今,这对医院药剂师来说是一个巨大的挑战,他们必须考虑与化学和物理稳定性相关的关键问题,除了微生物学问题外,还要确保高质量的制剂,保证护理的安全性和质量,保护患者及其健康。本文的目的是强调从住院环境过渡到门诊环境的关键问题,特别关注需要长期连续输注制备的化疗方案。