Yeum Tae-Sung, Lee Jung, Park Sung-Yeol, Joen Yaelim, Kim Bung-Nyun
Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Science, Seoul National University College of Medicine, Seoul, Korea.
Soa Chongsonyon Chongsin Uihak. 2019 Jul 1;30(3):127-131. doi: 10.5765/jkacap.180036.
Many neurologic disorders manifest as psychiatric symptoms. Anti-N-Methyl-D-Aspartate (NMDA) receptor encephalitis is an autoimmune disease of the brain characterized by numerous neurological and psychiatric features. Despite being rare, its prevalence is rapidly increasing and early management is critical in ensuring successful and sustainable recovery. Therefore, the illness should be considered as a differential diagnosis when clinically assessing patients. This report presents a case of a female child who was hospitalized for acute psychiatric manifestations, which was later confirmed as anti-NMDA receptor encephalitis. She recovered relatively successfully after combined neurological and psychiatric treatment. This report provides information on the clinical course of early onset anti-NMDA receptor encephalitis, including treatment strategy and prognosis.
许多神经系统疾病表现为精神症状。抗N-甲基-D-天冬氨酸（NMDA）受体脑炎是一种脑部自身免疫性疾病，具有众多神经和精神方面的特征。尽管该病罕见，但其患病率正在迅速上升，早期治疗对于确保成功和可持续的康复至关重要。因此，在对患者进行临床评估时应将该病视为鉴别诊断的考虑因素。本报告介绍了一名因急性精神症状住院的女童病例，后来被确诊为抗NMDA受体脑炎。经过神经和精神科联合治疗后，她恢复得相对顺利。本报告提供了早发性抗NMDA受体脑炎的临床病程信息，包括治疗策略和预后。
