De Venter Maud, Illegems Jela, Van Royen Rita, Sabbe Bernard G C, Moorkens Greta, Van Den Eede Filip
University Psychiatric Department, Campus Antwerp University Hospital (UZA), Edegem, Belgium.
Faculty of Medicine and Health Sciences, Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp (UA), Antwerp, Belgium.
Front Psychiatry. 2020 Jun 12;11:536. doi: 10.3389/fpsyt.2020.00536. eCollection 2020.
To examine the relationship between childhood trauma and the response to group cognitive-behavioural therapy (GCBT) for chronic fatigue syndrome (CFS).
A single cohort study conducted in an outpatient university referral center for CFS including a well-documented sample of adult patients meeting the CDC criteria for CFS and having received 9 to 12 months of GCBT. A mixed effect model was adopted to examine the impact of childhood trauma on the treatment response in general and over time. The main outcome measures were changes in fatigue, as assessed with the Checklist Individual Strength (total score), and physical functioning, as gauged with the Short Form 36 Health Survey subscale, with the scales being completed at baseline, immediately after treatment completion and after 1 year.
We included 105 patients with CFS. Childhood trauma was not significantly associated with the response to GCBT over time on level of fatigue or physical functioning.
Childhood trauma does not seem to have an effect on the treatment response to dedicated GCBT for CFS sufferers over time. Therefore, in the allocation of patients to this kind of treatment, a history of childhood trauma should not be seen as prohibitive.
探讨童年创伤与慢性疲劳综合征(CFS)患者对团体认知行为疗法(GCBT)反应之间的关系。
在一所大学门诊转诊中心针对CFS开展了一项单队列研究,纳入了符合美国疾病控制与预防中心(CDC)CFS标准且接受了9至12个月GCBT的成年患者的详细记录样本。采用混合效应模型来检验童年创伤对总体及随时间推移的治疗反应的影响。主要结局指标包括使用个人力量检查表(总分)评估的疲劳变化,以及使用简明健康调查问卷36项简短量表子量表衡量的身体功能,这些量表在基线、治疗结束后即刻以及1年后完成。
我们纳入了105例CFS患者。随着时间推移,童年创伤与GCBT在疲劳水平或身体功能方面的反应无显著关联。
随着时间推移,童年创伤似乎对CFS患者接受专门的GCBT治疗的反应没有影响。因此,在为患者分配此类治疗时,童年创伤史不应被视为禁忌。