Pauna Henrique F, Paparella Michael M, Cureoglu Sebahattin, Hyppolito Miguel A
Department of Otolaryngology-Head and Neck Surgery University of Minnesota Minneapolis Minnesota USA.
Department of Ophthalmology, Otolaryngology and Head and Neck Surgery Ribeirão Preto Faculty of Medicine (FMRP-USP) Ribeirão Preto São Paulo Brazil.
Laryngoscope Investig Otolaryngol. 2020 May 6;5(3):506-510. doi: 10.1002/lio2.383. eCollection 2020 Jun.
To demonstrate the cochlear turns area changes among patients with a history of meningitis, through otopatologic study.
We performed an analysis of the area of the bony cochlear turns and the cochlear lumen of the horizontal sections containing the modiolus and the area of the basal turn at the level of round window, in temporal bones obtained from patients with a history of meningitis and compared to a nondiseased control group.
The mean area of the bony walls and the lumen of all cochlear turns are reduced within the meningitis group. Patients who presented a time from the diagnosis of meningitis to death longer than 30 days had a significant reduction in the cochlear turns area, as compared to the control group.
Future studies may further correlate audiologic outcomes, cochlear volume, and cochlear area among patients with meningitis.
通过耳病理学研究，证实有脑膜炎病史患者的耳蜗螺旋区域变化。
我们对取自有脑膜炎病史患者颞骨中包含蜗轴的水平切片的骨蜗螺旋区域、蜗管腔以及圆窗水平的底转区域进行了分析，并与无疾病对照组进行比较。
脑膜炎组中所有蜗螺旋的骨壁和管腔平均面积均减小。与对照组相比，从脑膜炎诊断到死亡时间超过30天的患者，其蜗螺旋区域有显著减小。
未来的研究可能会进一步关联脑膜炎患者的听力学结果、耳蜗体积和耳蜗面积。
