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经鼻内镜入路治疗颅颈交界区疾病:耳鼻喉科医生的视角

Endoscopic endonasal approaches to the craniovertebral junction: The Otolaryngologist's perspective.

作者信息

Husain Qasim, Kim Matthew H, Hussain Ibrahim, Anand Vijay K, Greenfield Jeffrey P, Schwartz Theodore H, Kacker Ashutosh

机构信息

Department of Otolaryngology - Head & Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School - Boston, MA, USA.

Department of Otolaryngology - Head & Neck Surgery, Weill Cornell Medical College - New York, NY, USA.

出版信息

World J Otorhinolaryngol Head Neck Surg. 2020 Mar 16;6(2):94-99. doi: 10.1016/j.wjorl.2020.01.001. eCollection 2020 Jun.

Abstract

OBJECTIVE

To review indications and techniques for the endoscopic endonasal approach to the craniovertebral junction (CVJ), analyze postoperative outcomes, and discuss important technical considerations.

METHODS

A retrospective analysis was performed on all patients undergoing endonasal endoscopic approaches to the CVJ from May 2007 to June 2017. Demographic information, presenting symptoms, imaging results, treatment course, postoperative functional status, and follow-up were recorded.

RESULTS

There was a total of 30 patients in this series, with a mean follow-up of 11.7 months. The average age was 33.6 years (range, 5-75 years), with 18 females and 12 males. The majority of patients ( = 22, 73.3%) had Chiari malformation type 1 with basilar invagination and symptomatic cervicomedullary compression as the indication for surgery. Intraoperative cerebrospinal fluid leak (CSF) was noted in 3 cases of odontoid resection and a single case of skull base resection. There were no postoperative CSF leaks. Overall, 81% of patients resumed regular diet by post-operative day 2 (range, 0-8 days). Severe postoperative dysphagia occurred in two cases with one requiring gastrostomy tube placement and another utilizing total parenteral nutrition for support prior to eventual gastrostomy. On average, patients were extubated by postoperative day 0.93 (range 0-3 days), with 85% extubated by postoperative day 1. A tracheotomy was required in one patient.

CONCLUSION

The endonasal endoscopic approach is a valuable technique for access to the CVJ with minimal disruption of respiratory and alimentary function.

摘要

目的

回顾经鼻内镜入路至颅颈交界区(CVJ)的适应证和技术,分析术后结果,并讨论重要的技术要点。

方法

对2007年5月至2017年6月期间所有接受经鼻内镜入路至CVJ手术的患者进行回顾性分析。记录人口统计学信息、临床表现、影像学结果、治疗过程、术后功能状态及随访情况。

结果

本系列共有30例患者,平均随访11.7个月。平均年龄33.6岁(范围5 - 75岁),女性18例,男性12例。大多数患者(22例,73.3%)患有1型Chiari畸形合并基底凹陷及有症状的颈髓压迫,以此作为手术指征。在3例齿状突切除病例和1例颅底切除病例中术中发现脑脊液漏(CSF)。术后无脑脊液漏发生。总体而言,81%的患者在术后第2天(范围0 - 8天)恢复正常饮食。2例患者术后出现严重吞咽困难,其中1例需要放置胃造瘘管,另1例在最终行胃造瘘术前需采用全胃肠外营养支持。患者平均在术后第0.93天(范围0 - 3天)拔管,85%的患者在术后第1天拔管。1例患者需要行气管切开术。

结论

经鼻内镜入路是一种用于进入CVJ的有价值的技术,对呼吸和消化功能的干扰最小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f83/7296474/24a18849fd5f/gr1.jpg

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