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希腊一家三级护理医院中路邓葡萄球菌的流行病学及抗菌药物敏感性

Epidemiology and antimicrobial susceptibility of Staphylococcus lugdunensis in a Greek tertiary-care hospital.

作者信息

Kachrimanidou Melina, Malliou Petra, Meletis Georgios, Netsika Foteini, Mavrovouniotis Ilias, Protonotariou Efthymia, Skoura Lemonia

机构信息

First Department of Microbiology, Aristotle University of Thessaloniki, Medical School, Thessaloniki, Greece.

First Propedeutic Department of General Surgery, AHEPA University Hospital, Thessaloniki, Greece.

出版信息

New Microbiol. 2020 Jul;43(3):133-135. Epub 2020 Jun 29.

PMID:32596739
Abstract

Staphylococcus lugdunensis is considered more pathogenic than other coagulase-negative Staphylococci (CoNS), with its virulence resembling that of Staphylococcus aureus. We report a retrospective study of all S. lugdunensis infection cases during a 3.5-year period in a large tertiary university hospital in Greece. S.lugdunensis was susceptible to most tested antibiotics, although a high resistance percentage was found to clindamycin (27%) and erythromycin (25%). The susceptibility rate to penicillin was 49%, much lower than previously reported elsewhere, indicating that penicillin may not be an optimal treatment choice for S. lugdunensis infections in our region.

摘要

路邓葡萄球菌被认为比其他凝固酶阴性葡萄球菌(CoNS)更具致病性,其毒力与金黄色葡萄球菌相似。我们报告了一项对希腊一家大型三级大学医院3.5年期间所有路邓葡萄球菌感染病例的回顾性研究。路邓葡萄球菌对大多数测试抗生素敏感,尽管发现对克林霉素(27%)和红霉素(25%)的耐药率较高。对青霉素的敏感率为49%,远低于其他地方先前报道的水平,这表明青霉素可能不是我们地区路邓葡萄球菌感染的最佳治疗选择。

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