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比较腹腔镜与机器人辅助根治性膀胱切除术治疗膀胱癌的围手术期并发症

Comparing Perioperative Complications Between Laparoscopic and Robotic Radical Cystectomy for Bladder Cancer.

作者信息

Arora Amandeep, Pugliesi Felipe, Zugail Ahmed S, Moschini Marco, Pazeto Cristiano, Macek Petr, Stabile Armando, Lanz Camille, Mombet Annick, Bennamoun Mostefa, Sanchez-Salas Rafael, Cathelineau Xavier

机构信息

Department of Urology, Institut Mutualiste Montsouris, Paris, France.

Department of Urology, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.

出版信息

J Endourol. 2020 Oct;34(10):1033-1040. doi: 10.1089/end.2020.0112.

Abstract

Minimally invasive cystectomy is being increasingly performed, however, data comparing laparoscopic radical cystectomy (LRC) and robotic radical cystectomy (RRC) are scarce. We compared 30- and 90-day Clavien-Dindo Classification (CDC) complications between patients undergoing LRC and RRC at our center. We retrospectively evaluated 300 patients who underwent minimally invasive radical cystectomy from January 2007 to July 2019 and grouped them into LRC (112 patients) and RRC (188 patients). We compared the two groups for demographic variables, perioperative characteristics, and 30- and 90-day CDC overall, minor, and major complications. Multivariable logistic regression analysis was performed to identify variables that predict perioperative complications. The two groups were comparable for the duration of surgery (270 minutes in LRC 265 minutes in RRC) and rate of conversion to open surgery. The RRC cohort had a higher estimated blood loss (EBL) (675 mL 500 mL,  = 0.006), but the two groups had a comparable need for intraoperative transfusion. Patients undergoing RRC also had a shorter duration of hospital stay (13 days 14 days,  < 0.001). There was no difference between the two groups for 30- and 90-day CDC overall, minor, and major complications. The incidence of rehospitalization within 30 days ( = 0.1) and surgical reintervention ( = 0.5) was also comparable between the two groups. On multivariable logistic regression analysis, approach to cystectomy (RRC LRC) was not a significant predictor of 30-day CDC overall and major complications. LRC was associated with lesser EBL, whereas the hospital stay was shorter in patients undergoing RRC. The two approaches were comparable with each other for 30- and 90-day CDC overall, minor, and major complications. The choice between the two approaches should depend on availability and surgeon experience and preference, rather than any specific perioperative parameter.

摘要

目前,微创膀胱切除术的开展越来越多,然而,比较腹腔镜根治性膀胱切除术(LRC)和机器人辅助根治性膀胱切除术(RRC)的数据却很匮乏。我们比较了在本中心接受LRC和RRC治疗的患者30天和90天的Clavien-Dindo分类(CDC)并发症情况。我们回顾性评估了2007年1月至2019年7月期间接受微创根治性膀胱切除术的300例患者,并将他们分为LRC组(112例患者)和RRC组(188例患者)。我们比较了两组患者的人口统计学变量、围手术期特征以及30天和90天的CDC总体、轻微和严重并发症情况。进行多变量逻辑回归分析以确定预测围手术期并发症的变量。两组患者的手术时间(LRC组为270分钟,RRC组为265分钟)和转为开放手术的比例相当。RRC组的估计失血量(EBL)更高(675 mL对500 mL,P = 0.006),但两组患者术中输血的需求相当。接受RRC治疗的患者住院时间也更短(13天对14天,P < 0.001)。两组患者在30天和90天的CDC总体、轻微和严重并发症方面没有差异。两组患者30天内再次住院的发生率(P = 0.1)和手术再次干预的发生率(P = 0.5)也相当。在多变量逻辑回归分析中,膀胱切除术的方式(RRC对LRC)不是30天CDC总体和严重并发症的显著预测因素。LRC与较少的EBL相关,而接受RRC治疗的患者住院时间更短。两种手术方式在30天和90天的CDC总体、轻微和严重并发症方面相当。两种手术方式的选择应取决于设备的可用性以及外科医生的经验和偏好,而非任何特定的围手术期参数。

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