Associate Professor of Otolaryngology, ENT and Head & Neck Research Center and Department, The Five Senses Institute, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
Assistant Professor of Otolaryngology, ENT and Head and Neck Research Center and Department, Iran University of Medical Sciences, Tehran, Iran.
Ann Otol Rhinol Laryngol. 2021 Jan;130(1):32-37. doi: 10.1177/0003489420934506. Epub 2020 Jun 29.
Pharyngocutaneous fistula (PCF) is one of the most severe multifactorial complications following laryngectomy. The current study aimed at determining the effect of a low-pressure vacuum drain on the incidence of PCF after total laryngectomy.
The current randomized clinical trial was conducted on 35 patients undergoing total laryngectomy in Hazrat Rasoul Akram and Firoozgar hospitals in Tehran, Iran. The subjects were divided into the vacuum drain (n = 15) and control (without vacuum drain) (n = 20) groups. The incidence of PCF and the recovery time were recorded.
The rate of PCF formation from the stoma and wound edges was significantly lower in the low-pressure vacuum drain group than in the control group (6.7% vs 40%) ( < .05). There was no significant difference between the groups in time to recovery from PCF.
The low-pressure vacuum drain method is effective in reducing the incidence of PCF after total laryngectomy.
咽皮瘘（PCF）是喉切除术后最严重的多因素并发症之一。本研究旨在确定低压真空引流对全喉切除术后 PCF 发生率的影响。
本随机临床试验在伊朗德黑兰的拉苏尔阿克拉姆和菲罗兹加尔医院对 35 例接受全喉切除术的患者进行。受试者分为真空引流组（n=15）和对照组（无真空引流）（n=20）。记录 PCF 的发生率和恢复时间。
与对照组（40%）相比，低压真空引流组发生吻合口和伤口边缘 PCF 的比例明显更低（6.7%）（<0.05）。两组从 PCF 恢复的时间无显著差异。
低压真空引流法可有效降低全喉切除术后 PCF 的发生率。
