Sy Marie Charmaine C, Espiritu Adrian I, Sy Matthew Samuel C, Jamora Roland Dominic G, Anlacan Veeda Michelle M
Department of Neurosciences, Division of Adult Neurology, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Department of Clinical Epidemiology, College of Medicine, University of the Philippines Manila, Manila, Philippines.
J Alzheimers Dis. 2020;76(3):1151-1160. doi: 10.3233/JAD-200355.
Scientific output in Southeast Asia (SEA) on the topic of dementia is postulated to be low in quality and quantity. It is also speculated that certain socioeconomic variables and measures of disease burden for dementia may play a significant role in driving the research output of a particular country.
This study aimed to determine the research impact of published journal articles on dementia in SEA and its association with country-level socioeconomic factors and measures of disease burden for dementia.
A systematic search was conducted using electronic healthcare databases. We included articles published on dementia until August 2019 with at least 1 author affiliated with any SEA institution. We obtained bibliometric indices, relevant socioeconomic factors, and measures of disease burden for dementia from published sources.
One thousand six articles fulfilled the inclusion criteria. The majority of publications were related to Alzheimer's disease (n = 775, 77.0%). Singapore contributed the highest number of publications (n = 457, 45.4%). Gross domestic product (GDP) per capita, % GDP for research and development, and total neurologists significantly correlated with several bibliometric indices. On the other hand, the measures of disease burden for dementia in SEA countries were not significantly associated with research productivity.
Research productivity in SEA on dementia has substantially increased in recent years. Augmenting GDP per capita and expanding the apportionment of resources to research and development (R&D) may have a significant role in the advancement of dementia research in SEA.
据推测，东南亚（SEA）关于痴呆症主题的科学产出在质量和数量上都很低。也有人猜测，某些社会经济变量和痴呆症疾病负担指标可能在推动特定国家的研究产出方面发挥重要作用。
本研究旨在确定东南亚已发表的关于痴呆症的期刊文章的研究影响力及其与国家层面社会经济因素和痴呆症疾病负担指标的关联。
使用电子医疗数据库进行系统检索。我们纳入了截至2019年8月发表的、至少有1位作者隶属于任何东南亚机构的关于痴呆症的文章。我们从已发表的资料中获取文献计量指标、相关社会经济因素和痴呆症疾病负担指标。
1600篇文章符合纳入标准。大多数出版物与阿尔茨海默病相关（n = 775，77.0%）。新加坡的出版物数量最多（n = 457，45.4%）。人均国内生产总值（GDP）、研发占GDP的百分比以及神经科医生总数与几个文献计量指标显著相关。另一方面，东南亚国家的痴呆症疾病负担指标与研究生产力没有显著关联。
近年来，东南亚关于痴呆症的研究生产力大幅提高。提高人均GDP以及扩大对研发的资源分配可能在东南亚痴呆症研究的推进中发挥重要作用。
