Mikami Tatsuya, Ichikawa Tamaki, Kazama Toshiki, Aoyama Yasuyuki, Mabuchi Tomotaka, Ikoma Haruka, Kajiwara Hiroshi, Nagafuji Yui, Sekiguchi Yuka, Kodama Eriko, Fukuzawa Tsuyoshi, Kuroki Toshihisa, Nagao Ryouta, Hashimoto Jun
Department of Radiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Tokai J Exp Clin Med. 2020 Jul 20;45(2):58-62.
Here, we report the case of cutaneous metastases from testicular diffuse large B-cell malignant lymphoma (DLBCL) concurrent with Bowen disease evaluated with 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT). A 60-year-old male underwent orchiectomy to remove his left testicle because of DLBCL. Multiple skin lesions appeared 1 month postoperatively. Furthermore, an intractable erythematous plaque localized to the right lower leg was present from 2 years before the operation. 18F-FDG PET-CT images revealed multiple skin lesions with marked FDG uptakes in the face, neck, and thigh of this patient, as well as a lower leg lesion with minimal FDG uptake. Biopsy of both lesions revealed cutaneous metastases from DLBCL and Bowen disease (BD) of the lower leg lesion. 18F-FDG PET-CT images following chemotherapy and resection of BD demonstrated no FDG uptake.
在此,我们报告一例睾丸弥漫性大B细胞恶性淋巴瘤(DLBCL)皮肤转移并发鲍恩病的病例,该病例采用18F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描(18F-FDG PET-CT)进行评估。一名60岁男性因DLBCL接受了左侧睾丸切除术。术后1个月出现多处皮肤病变。此外,术前2年右小腿出现一处难治性红斑斑块。18F-FDG PET-CT图像显示该患者面部、颈部和大腿有多处皮肤病变,FDG摄取明显,小腿病变FDG摄取极少。对两处病变进行活检,结果显示小腿病变为DLBCL皮肤转移和鲍恩病(BD)。化疗及切除BD后的18F-FDG PET-CT图像显示无FDG摄取。