正在接受其他治疗的 COVID-19 患者，在使用目前提议用于 COVID-19 治疗的药物时，可能会发生药物-药物相互作用。
Potential drug-drug interactions associated with drugs currently proposed for COVID-19 treatment in patients receiving other treatments.
机构信息
Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Rennes, F-35000, France.
INSERM, Centre d'Investigation Clinique, CIC 1414, Rennes, F-35000, France.
出版信息
Fundam Clin Pharmacol. 2020 Oct;34(5):530-547. doi: 10.1111/fcp.12586. Epub 2020 Jul 24.
Abstract
Patients with COVID-19 are sometimes already being treated for one or more other chronic conditions, especially if they are elderly. Introducing a treatment against COVID-19, either on an outpatient basis or during hospitalization for more severe cases, raises the question of potential drug-drug interactions. Here, we analyzed the potential or proven risk of the co-administration of drugs used for the most common chronic diseases and those currently offered as treatment or undergoing therapeutic trials for COVID-19. Practical recommendations are offered, where possible.
摘要
患有 COVID-19 的患者有时已经在接受一种或多种其他慢性疾病的治疗，尤其是如果他们是老年人。对于门诊或更严重病例住院治疗的 COVID-19 患者，引入一种治疗方法会引发潜在的药物相互作用的问题。在这里，我们分析了最常见的慢性疾病药物和目前作为 COVID-19 治疗或正在进行治疗试验的药物联合使用的潜在或已证实的风险。在可能的情况下提供了实用建议。
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