白细胞介素2与淋巴因子激活的杀伤细胞治疗恶性肿瘤
[Treatment of malignant tumors by interleukin 2 and LAK cells].
作者信息
Degos L
机构信息
Service d'Hématologie, Hôpital Saint-Louis, Paris, France.
出版信息
Nouv Rev Fr Hematol (1978). 1988;30(1-2):119-22.
PMID:3260373
Abstract
Lymphokine-activated killer (LAK) cells are cells able to lyse fresh tumor cells. In vivo treatment using LAK cells and interleukin 2 is highly toxic because of increased capillary permeability. International discussion is underway on this promising or too toxic therapy. However, such treatment opens a new way for ex vivo manipulation of cells.
摘要
淋巴因子激活的杀伤细胞（LAK细胞）是能够裂解新鲜肿瘤细胞的细胞。由于毛细血管通透性增加，使用LAK细胞和白细胞介素2进行体内治疗毒性很大。关于这种有前景或毒性过大的疗法的国际讨论正在进行中。然而，这种治疗为细胞的体外操作开辟了一条新途径。
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