8个国家男性勃起功能障碍对性规划行为以及健康和治疗相关结果影响的真实世界评估
Real-World Assessment of the Impact of Erectile Dysfunction on Sexual Planning Behavior and Health- and Treatment-Related Outcomes Among Men in 8 Countries.
作者信息
Goldstein Irwin, Giraldi Annamaria, Maculaitis Martine C, Li Vicky W, Hartzell-Cushanick Rose, Hassan Tarek A
机构信息
Sexual Medicine, Alvarado Hospital, San Diego, CA, USA.
Sexological Clinic, Psychiatric Centre Copenhagen, Copenhagen, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
出版信息
Sex Med. 2020 Sep;8(3):338-349. doi: 10.1016/j.esxm.2020.05.001. Epub 2020 Jun 27.
INTRODUCTION
The effect of erectile dysfunction (ED) on sexual planning behaviors and outcomes in men taking phosphodiesterase type 5 inhibitors (PDE5Is) is not well studied.
AIMS
To assess sexual habits, behaviors, and treatment-related outcomes of PDE5I-treated men with ED.
METHODS
This cross-sectional observational study recruited men aged 30 to 70 years with mild-to-severe ED from 8 diverse countries (the United States, the United Kingdom, Italy, Russia, Turkey, Israel, China, and Japan) to complete an approximately 15-minute survey. Differences were evaluated using bivariate analyses, and data were summarized using descriptive statistics.
MAIN OUTCOME MEASURES
Self-reported data were collected for demographics, health characteristics, treatment, sexual habits, ED severity, ED-specific quality of life, and treatment satisfaction.
RESULTS
The survey was completed by 1,575 men. Mean frequency of sexual intercourse was 5.7 times/month. Overall, 87.1% of men always, often, or sometimes planned for sexual activity. Of those planning in advance, 32.8% and 40.6% agreed or strongly agreed that they plan for specific days of the week and times of day, respectively. Sexual planning habits were similar for patients taking short-acting vs long-acting PDE5Is. The most commonly cited reasons for planning sexual activity were needing time to take medication (48.4%), needing to make sure medication has taken effect (43.4%), convenient time for sexual activity (34.9%), and needing the partner's agreement (33.4%). Mean Self-Esteem and Relationship Questionnaire total score was 56.4.
CONCLUSIONS
The differences in ED burden and sexual planning behavior observed across countries were not influenced by the type of PDE5I being taken, suggesting that cultural differences are an important factor when considering types of ED treatment. These findings provide a better understanding of burden, sexual habits, planning behaviors, quality of life, and treatment-related outcomes among PDE5I-treated men with ED in 8 Western and non-Western countries and may aid healthcare providers in selecting optimal treatments. Goldstein I, Giraldi A, Maculaitis MC, Real-World Assessment of the Impact of Erectile Dysfunction on Sexual Planning Behavior and Health- and Treatment-Related Outcomes Among Men in 8 Countries. J Sex Med 2020;8:338-349.
引言
勃起功能障碍（ED）对服用5型磷酸二酯酶抑制剂（PDE5Is）的男性的性计划行为及结果的影响尚未得到充分研究。
目的
评估接受PDE5I治疗的ED男性的性习惯、行为及与治疗相关的结果。
方法
这项横断面观察性研究招募了来自8个不同国家（美国、英国、意大利、俄罗斯、土耳其、以色列、中国和日本）年龄在30至70岁之间患有轻至重度ED的男性，让他们完成一份约15分钟的调查问卷。采用双变量分析评估差异，并用描述性统计方法汇总数据。
主要观察指标
收集有关人口统计学、健康特征、治疗、性习惯、ED严重程度、ED特异性生活质量及治疗满意度的自我报告数据。
结果
1575名男性完成了调查。性交的平均频率为每月5.7次。总体而言，87.1%的男性总是、经常或有时会计划性活动。在那些提前计划的人中，分别有32.8%和40.6%的人同意或强烈同意他们会计划一周中的特定日子和一天中的特定时间。服用短效与长效PDE5I的患者的性计划习惯相似。计划性活动最常提及的原因是需要时间服药（48.4%）、需要确保药物起效（43.4%）、性活动的方便时间（34.9%）以及需要伴侣同意（33.4%）。自尊与关系问卷总分的平均值为56.4。
结论
在不同国家观察到的ED负担和性计划行为的差异不受所服用PDE5I类型的影响，这表明在考虑ED治疗类型时文化差异是一个重要因素。这些发现有助于更好地了解8个西方和非西方国家中接受PDE5I治疗的ED男性的负担、性习惯、计划行为、生活质量及与治疗相关的结果，并可能有助于医疗保健提供者选择最佳治疗方法。戈尔茨坦I，吉拉尔迪A，马库莱蒂斯MC，8个国家男性勃起功能障碍对性计划行为及健康和治疗相关结果影响的真实世界评估。《性医学杂志》2020年；8：338 - 349。
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