Università Vita-Salute San Raffaele, Milan, Italy; IRCCS San Raffaele Hospital, Milan, Italy.
Dipartimento di Medicina e Chirurgia, University Hospital of Parma, Parma, Italy.
Nutr Metab Cardiovasc Dis. 2020 Aug 28;30(9):1427-1441. doi: 10.1016/j.numecd.2020.05.004. Epub 2020 May 21.
Chronic metabolic alterations such as post-transplant diabetes mellitus (PTDM), dyslipidaemias and overweight/obesity significantly impact on kidney transplant (KT) outcomes. This joint position statement is based on the evidence on the management of metabolic alterations in KT recipients (KTRs) published after the release of the 2009 KDIGO clinical practice guideline for the care of KTRs. Members of the Italian Society of Nephrology (SIN), the Italian Society for Organ Transplantation (SITO) and the Italian Diabetes Society (SID) selected to represent professionals involved in the management of KTRs undertook a systematic review of the published evidence for the management of PTDM, dyslipidaemias and obesity in this setting. The aim of this work is to provide an updated review of the evidence on the prevention, diagnosis and treatment of metabolic alterations in KTRs, in order to support physicians, patients and the Healthcare System in the decision-making process when choosing among the various available options.
慢性代谢改变，如移植后糖尿病（PTDM）、血脂异常和超重/肥胖，对肾移植（KT）结局有显著影响。本联合立场声明基于 2009 年 KDIGO 肾移植受者护理临床实践指南发布后发表的关于 KT 受者（KTR）代谢改变管理的证据。意大利肾脏病学会（SIN）、意大利器官移植学会（SITO）和意大利糖尿病学会（SID）的成员代表参与 KTR 管理的专业人员，对 PTDM、血脂异常和肥胖在这一领域的管理进行了系统的文献回顾。这项工作的目的是提供 KTR 代谢改变预防、诊断和治疗的最新证据综述，以在选择各种可用方案时为医生、患者和医疗保健系统提供决策支持。
