Department of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece.
Research Institute of Animal Science/Hellenic Agricultural Organization Demeter, Giannitsa, Greece.
In Vivo. 2020 Jul-Aug;34(4):1811-1821. doi: 10.21873/invivo.11976.
BACKGROUND/AIM: Olive mill wastewater (OMW) is a byproduct of olive oil production. The aim of the study was to estimate the redox profile of lambs' vital organs after consumption of an OMW-supplemented feed.
Twenty-four lambs received breast milk until day 15. Then, they were divided in two groups: control and OMW, n=12 each. The control group received standard ration, while the OMW group received OMW enriched feed along with mother's milk until day 42 and animals (n=6 per group) were sacrificed. The remaining 12 received the feeds until day 70 and sacrificed. Tissue samples were collected at day 42 and 70 and specific redox biomarkers were assessed.
Overall, the OMW feed improved tissue redox profile by affecting the glutathione S-transferase (GST) activity and γ-glutamate-cysteine ligase (γ-GCL) expression in all tested tissues. Superoxide dismutase (SOD) activity was not affected.
The polyphenol-rich byproduct reinforced lamb redox profile and may putatively improve their wellness and productivity.
背景/目的:橄榄厂废水(OMW)是橄榄油生产的副产品。本研究的目的是评估摄入富含橄榄厂废水的饲料后羔羊重要器官的氧化还原状态。
24 只羔羊在 15 日龄前接受母乳。然后,将它们分为两组:对照组和 OMW 组,每组 12 只。对照组接受标准饲料,而 OMW 组则在哺乳期接受富含 OMW 的饲料,直到第 42 天,然后对动物(每组 6 只)进行安乐死。其余 12 只继续接受饲料,直到第 70 天并进行安乐死。在第 42 天和第 70 天采集组织样本,并评估特定的氧化还原生物标志物。
总体而言,OMW 饲料通过影响所有测试组织中的谷胱甘肽 S-转移酶(GST)活性和γ-谷氨酰半胱氨酸连接酶(γ-GCL)表达,改善了组织的氧化还原状态。超氧化物歧化酶(SOD)活性不受影响。
富含多酚的副产物增强了羔羊的氧化还原状态,并可能潜在地提高它们的健康和生产力。