Department of Ophthalmology, University Medical Center Rostock, Rostock, Germany
Institute of Pathology, University Medical Center Rostock, Rostock, Germany.
In Vivo. 2020 Jul-Aug;34(4):1965-1974. doi: 10.21873/invivo.11993.
To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL).
A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018.
OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large B-cell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048).
Our data suggest that clinicopathological features such as Ann Arbor stage influence survival.
评估眼附属器淋巴瘤（OAL）的生物数据、症状/体征、淋巴瘤类型、定位、分期水平、治疗选择和结果。
对 1998 年至 2018 年期间在单中心接受治疗的 56 例 OAL 患者进行回顾性分析。
OAL 累及眼眶占 44.6%，结膜占 32.1%，泪器占 14.3%，眼睑占 8.93%。边缘区 B 细胞淋巴瘤（EMZL）占 60.7%，滤泡性淋巴瘤（FL）占 21.4%，弥漫性大 B 细胞淋巴瘤占 7.14%，套细胞淋巴瘤占 5.36%，慢性淋巴细胞白血病占 5.36%。76%的患者无复发。EMZL 和 FL 的总生存率明显优于其他淋巴瘤类型（p=0.002）。Ann Arbor 分期为 IE 的患者预后明显优于分期高于 IE 的患者（p=0.048）。
我们的数据表明，临床病理特征如 Ann Arbor 分期影响生存。
