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一例肉芽肿性唇炎/口面部肉芽肿病

A Case of Cheilitis Granulomatosa/Orofacial Granulomatosis.

作者信息

Brown Ronald, Farquharson Andre, Cherry-Peppers Gail, Lawrence Leslie, Grant-Mills Donna

机构信息

Department of Oral Diagnosis & Radiology, Howard University College of Dentistry, Washington, DC, USA.

Department of Restorative Dentistry, Howard University College of Dentistry, Washington, DC, USA.

出版信息

Clin Cosmet Investig Dent. 2020 Jun 23;12:219-224. doi: 10.2147/CCIDE.S254899. eCollection 2020.

DOI:10.2147/CCIDE.S254899
PMID:32606993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7320889/
Abstract

A case of a 19-year-old female patient is presented to a private practice dental clinician with swelling of the lower lip and inflammation of the anterior dorsal tongue. The patient presented with moderate oral pain as well as abdominal pain. The lesions were biopsied and noted for a granulomatous histopathologic appearance. The patient reported a history of using cinnamon as a flavoring agent. The lesions resolved within two weeks after the biopsy procedures and topical steroid therapy. The lesions were diagnosed as cheilitis granulomatosa/orofacial granulomatosis. The patient has remained lesion free as of the three-year follow-up. Etiologic, diagnostic and therapeutic issues related to this relatively rare condition of cheilitis granulomatosa/orofacial granulomatosis are discussed.

摘要

一名19岁女性患者因下唇肿胀和舌背前部炎症就诊于一名私人执业牙科临床医生。患者伴有中度口腔疼痛和腹痛。对病变进行活检,组织病理学表现为肉芽肿性。患者报告有使用肉桂作为调味剂的病史。活检和局部类固醇治疗后两周内病变消退。病变被诊断为肉芽肿性唇炎/口面部肉芽肿病。截至三年随访,患者一直无病变。本文讨论了与这种相对罕见的肉芽肿性唇炎/口面部肉芽肿病相关的病因、诊断和治疗问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/eaea258f66c9/CCIDE-12-219-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/56cc8b8dfdce/CCIDE-12-219-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/f801970fe986/CCIDE-12-219-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/566bcfbf389e/CCIDE-12-219-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/d27cb98d8b3e/CCIDE-12-219-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/eaea258f66c9/CCIDE-12-219-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/56cc8b8dfdce/CCIDE-12-219-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/f801970fe986/CCIDE-12-219-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/566bcfbf389e/CCIDE-12-219-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/d27cb98d8b3e/CCIDE-12-219-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922a/7320889/eaea258f66c9/CCIDE-12-219-g0005.jpg

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本文引用的文献

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A Systematic Review of the Literature of the Three Related Disease Entities Cheilitis Granulomatosa, Orofacial Granulomatosis and Melkersson - Rosenthal Syndrome.唇部肉芽肿性唇炎、口面部肉芽肿病和梅克尔森-罗森塔尔综合征这三种相关疾病实体的文献系统评价
Curr Pediatr Rev. 2018;14(3):196-203. doi: 10.2174/1573396314666180515113941.
2
Orofacial granulomatosis.口面部肉芽肿病
Clin Dermatol. 2016 Jul-Aug;34(4):505-13. doi: 10.1016/j.clindermatol.2016.02.024. Epub 2016 Mar 3.
3
Azathioprine is effective for oral involvement in Crohn's disease but not for orofacial granulomatosis alone.
硫唑嘌呤对克罗恩病的口腔病变有效,但对单独的口面部肉芽肿病无效。
J Oral Pathol Med. 2016 Apr;45(4):312-8. doi: 10.1111/jop.12379. Epub 2015 Nov 23.
4
Orofacial Granulomatosis.口面部肉芽肿病
Dermatol Clin. 2015 Jul;33(3):433-46. doi: 10.1016/j.det.2015.03.008. Epub 2015 May 6.
5
Orofacial granulomatosis: clinical signs of different pathologies.口腔面部肉芽肿病:不同病理的临床征象。
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