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Tuberculosis in the Elderly.老年人结核病
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Profile and treatment outcomes of elderly patients with tuberculosis in Delhi, India: implications for their management.印度德里老年结核病患者的概况及治疗结果:对其管理的启示
Trans R Soc Trop Med Hyg. 2013 Dec;107(12):763-8. doi: 10.1093/trstmh/trt094. Epub 2013 Nov 4.
2
The profile and treatment outcomes of the older (aged 60 years and above) tuberculosis patients in Tamilnadu, South India.印度南部泰米尔纳德邦老年(60 岁及以上)结核病患者的特征和治疗结果。
PLoS One. 2013 Jul 8;8(7):e67288. doi: 10.1371/journal.pone.0067288. Print 2013.
3
Manifestations of tuberculosis in elderly versus young hospitalised patients in Amritsar, India.印度阿姆利则老年与年轻住院患者结核病表现。
Int J Tuberc Lung Dis. 2012 Sep;16(9):1210-3. doi: 10.5588/ijtld.11.0778. Epub 2012 Jul 12.
4
Factors influencing time to smear conversion in patients with smear-positive pulmonary tuberculosis.影响涂片阳性肺结核患者涂片转阴时间的因素。
Respirology. 2009 Sep;14(7):1012-9. doi: 10.1111/j.1440-1843.2009.01598.x. Epub 2009 Jul 30.
5
Manifestations of pulmonary tuberculosis in the elderly: a prospective observational study from north India.老年人肺结核的表现:来自印度北部的一项前瞻性观察研究。
Indian J Chest Dis Allied Sci. 2008 Jul-Sep;50(3):263-7.
6
Clinico-radiological profile of new smear positive pulmonary tuberculosis cases among young adult and elderly people in a tertiary care hospital at Deheradun (Uttarakhand).北阿坎德邦德拉敦市一家三级护理医院中青年和老年人中新涂片阳性肺结核病例的临床放射学特征
Indian J Tuberc. 2008 Apr;55(2):84-90.
7
[Clinical aspects of pulmonary tuberculosis in elderly patients from a university hospital in Rio de Janeiro, Brazil].[巴西里约热内卢一家大学医院老年患者肺结核的临床特征]
J Bras Pneumol. 2007 Nov-Dec;33(6):699-706. doi: 10.1590/s1806-37132007000600014.
8
The prevalence and evolution of anemia associated with tuberculosis.与结核病相关的贫血的患病率及演变情况。
J Korean Med Sci. 2006 Dec;21(6):1028-32. doi: 10.3346/jkms.2006.21.6.1028.
9
Diagnostic and therapeutic problems of pulmonary tuberculosis in elderly patients.老年患者肺结核的诊断与治疗问题
J Korean Med Sci. 2005 Oct;20(5):784-9. doi: 10.3346/jkms.2005.20.5.784.
10
Tuberculosis in older people: a retrospective and comparative study from Hong Kong.老年人肺结核:一项来自香港的回顾性比较研究。
J Am Geriatr Soc. 2002 Jul;50(7):1219-26. doi: 10.1046/j.1532-5415.2002.50308.x.

新诊断痰涂片阳性肺结核老年患者与青年患者临床、影像学和实验室参数比较:一项基于医院的横断面研究

Comparison of Clinical, Radiological and Laboratory Parameters Between Elderly and Young Patient With Newly Diagnosed Smear Positive Pulmonary Tuberculosis: A Hospital-Based Cross Sectional Study.

作者信息

Rajaram Manju, Malik Archana, Mohanty Mohapatra Madhusmita, Vijayageetha Mathavaswami, Mahesh Babu Vemuri, Vally Soundara, Saka Vinod Kumar

机构信息

Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Internal Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

出版信息

Cureus. 2020 May 27;12(5):e8319. doi: 10.7759/cureus.8319.

DOI:10.7759/cureus.8319
PMID:32607302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7320658/
Abstract

Introduction To compare clinical, radiological and haematological manifestations among newly diagnosed smear positive tuberculosis patients between Group I (Elderly >60 yrs) and Group II (Younger age between 13 and 60 years). Methodology This was a hospital-based cross-sectional study conducted at the out-patient department of pulmonary medicine, between March 2014 and December 2017. There were 61 patients in Group I (Elderly > 60 yrs) and 110 patients in Group II (Younger age between 13 and 60 years). Continuous variables were compared using student's t-test and Mann-Whitney test. Chi square test and Fischer test was used for analysing categorical variables. All statistics were two-tailed, and a p-value of 0.05 was considered to be statistically significant. Results The mean age for Group I (Elderly >60 yrs) was 65 ± 2 years and for the Group II (Younger age between 13 and 60 years) was 40 ± 1 years. There was a statistically significant association of cavitation with infiltrates (p = 0.007) in younger age group. Bilateral multiple zone (48, 64.86%) involvements were commonly observed in both the age groups. There was no significant difference between two groups with regard to haematological and clinical parameters. Conclusion We did not find any difference in the presentation of tuberculosis in both the groups. Radiologically, there was more of cavitating lesion in younger age group. So, they should be isolated and followed up at regular intervals.

摘要

引言

比较第一组(年龄>60岁的老年人)和第二组(年龄在13至60岁之间的年轻人)新诊断的涂片阳性肺结核患者的临床、放射学和血液学表现。

方法

这是一项于2014年3月至2017年12月在肺科门诊进行的基于医院的横断面研究。第一组(年龄>60岁的老年人)有61例患者,第二组(年龄在13至60岁之间的年轻人)有110例患者。连续变量采用学生t检验和曼-惠特尼检验进行比较。卡方检验和费舍尔检验用于分析分类变量。所有统计均为双侧检验,p值<0.05被认为具有统计学意义。

结果

第一组(年龄>60岁的老年人)的平均年龄为65±2岁,第二组(年龄在13至60岁之间的年轻人)的平均年龄为40±1岁。在较年轻年龄组中,空洞与浸润之间存在统计学显著关联(p = 0.007)。两个年龄组均常见双侧多区域受累(48例,64.86%)。两组在血液学和临床参数方面无显著差异。

结论

我们未发现两组肺结核表现有任何差异。放射学上,较年轻年龄组空洞性病变更多。因此,应对他们进行隔离并定期随访。