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回复对“DCC 多态性与自闭症谱系障碍易感性的关联”一文的评论。

Reply to Comment on "Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder".

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, 130021, China.

Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, 130021, China.

出版信息

J Autism Dev Disord. 2020 Oct;50(10):3811-3812. doi: 10.1007/s10803-020-04585-2.

Abstract

The comments from Dr. Meisami about our article "Association between DCC polymorphisms and Susceptibility to Autism Spectrum Disorder", and we wish to respond to several points. First, 100% of detection rate for each SNP genotype cannot be obtained. Second, we listed the detection rates in Supplemental Table 1. Last, Dr. Meisami referred an article focused on two SNPs; however, our article focused on seven SNPs. If we marked the number of detected cases, we had to make a table for each result, occupying a large part of the layout. Moreover, if the number of detected cases was marked respectively, it was not in accordance with academic norms. For these reasons, we provided the actual number of cases in Table 3.

摘要

迈萨米博士对我们的文章“DCC 多态性与自闭症谱系障碍易感性的关联”发表了评论,我们希望对此做出几点回应。首先,无法获得每个 SNP 基因型的 100%检测率。其次,我们在补充表 1 中列出了检测率。最后,迈萨米博士提到了一篇专注于两个 SNP 的文章;然而,我们的文章专注于七个 SNP。如果我们标记每个 SNP 基因型的检测案例数,我们必须为每个结果制作一个表格,这将占据布局的很大一部分。此外,如果分别标记检测案例数,这不符合学术规范。出于这些原因,我们在表 3 中提供了实际案例数。

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