Goltz Diane, Fischer Hans-Peter
Pathologisches Institut Koblenz, Franz-Weis-Str. 13, 56073, Koblenz, Deutschland.
Institut für Pathologie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland.
Pathologe. 2020 Sep;41(5):471-477. doi: 10.1007/s00292-020-00802-y.
This review covers a spectrum of pathologic changes and diseases involving hepatic sinusoids. In the majority of patients, clinical findings are rather uncharacteristic such as hepatomegaly, portal hypertension, or lingering liver failure of unknown origin. In contrast to more common hepatic disorders, characteristic clinical, serological, immunoserological, and radiographical findings are lacking. In these cases, biopsy findings may be crucial to guide treatment decisions. This review covers a variety of hepatic disorders that practicing pathologists may encounter in their clinical routine.
本综述涵盖了一系列涉及肝血窦的病理变化和疾病。在大多数患者中，临床表现相当不典型，如肝肿大、门静脉高压或原因不明的持续性肝衰竭。与更常见的肝脏疾病相比，缺乏特征性的临床、血清学、免疫血清学和影像学表现。在这些情况下，活检结果对于指导治疗决策可能至关重要。本综述涵盖了执业病理学家在临床日常工作中可能遇到的各种肝脏疾病。
