Oncology (Williston Park). 2020 Jun 10;34(6):211-215.
LP strategies should be considered only in patients with resectable stage III/IV larynx and hypopharynx SCC, ideally those who have a functional larynx. The choice of treatment must be discussed by a multidisciplinary team, and the patient must have an active role in making the decision. CRT and IC-RT are both approved larynx-preservation approaches. IC-RT has demonstrated high rates of LP without decreasing DFS or OS, compared with surgery. CRT has demonstrated better LP rates, as well as local control and LRC, compared with IC-RT, and it should be considered a standard of care.
LP 策略应仅考虑在可切除的 III/IV 期喉和声门下鳞状细胞癌患者中实施，理想情况下是那些保留有功能喉的患者。治疗选择必须由多学科团队讨论，患者必须在做出决策中发挥积极作用。CRT 和 IC-RT 都是被批准的保留喉方法。与手术相比，IC-RT 显示出较高的 LP 率，同时不降低DFS 或 OS。CRT 与 IC-RT 相比，显示出更好的 LP 率、局部控制和 LRC，应被视为标准治疗。
