Bustamante R, Thivolet J, Claudy A
Ann Dermatol Venereol. 1977 Feb;104(2):93-7.
The authors report 10 cases of selected Gougerot-Ruiter's disease and 13 cases of various vasculitis. Direct immunofluorescence studies were performed on the skin lesions and the results were correlated to various biological parameters such as dosage of serum IgA, IgG and IgM, antinuclear antibodies, Australia antigen. Complement (beta-1-C/beta-1-A) deposition was found in 9 out of 10 cases of Gougerot-Ruiter's disease as opposed to immunoglobulin deposition found only in 4 out of 10 cases. Both C3 and immunoglobin were regularly found in the vessel walls of 2 cases of cryoglobulinemia and 1 case of SLE. In the cases of thrombopenic purpura, simplex purpura. Schoenlein Henoch purpura and drug induced purpura, complement (beta-1-C/beta-1-A) and immunoglobulin were absent in the lesions. The authors discuss the different physiopathological mechanisms which may be involved in the development of Gougerot-Ruiter's vasculitis.
作者报告了10例经挑选的 Gougerot-Ruiter 病病例和13例各种血管炎病例。对皮肤病变进行了直接免疫荧光研究，并将结果与各种生物学参数相关联，如血清IgA、IgG和IgM的剂量、抗核抗体、澳大利亚抗原。在10例Gougerot-Ruiter病病例中，9例发现有补体（β-1-C/β-1-A）沉积，而10例中只有4例发现有免疫球蛋白沉积。在2例冷球蛋白血症和1例系统性红斑狼疮病例的血管壁中均定期发现C3和免疫球蛋白。在血小板减少性紫癜、单纯性紫癜、舍恩莱因-亨诺紫癜和药物性紫癜病例中，病变部位不存在补体（β-1-C/β-1-A）和免疫球蛋白。作者讨论了可能与Gougerot-Ruiter血管炎发展有关的不同生理病理机制。
