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抗精神病药物的使用:土耳其儿童和青少年精神科医生的经验、观点和监测实践。

Use of Antipsychotics: The Experiences, Views, and Monitoring Practices of Child and Adolescent Psychiatrists in Turkey.

机构信息

Department of Child and Adolescent Psychiatry, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey.

出版信息

J Child Adolesc Psychopharmacol. 2021 Feb;31(1):73-78. doi: 10.1089/cap.2020.0078. Epub 2020 Jun 30.

DOI:10.1089/cap.2020.0078
PMID:32614261
Abstract

The aim of this study is to evaluate the antipsychotics prescribed by child psychiatrists and their applications on the follow-up of these drugs. The universe of this research included consultant physicians and child psychiatry residents working in the field. A questionnaire has been created that assesses the use of antipsychotics and follow-up processes of physicians. The survey involved 19 questions. Contents of the survey were sociodemographic data, short-term and long-term follow-up of antipsychotic drugs, side-effect intervention strategies, and diagnoses of the most commonly preferred antipsychotic medications. The survey was delivered via e-mail and sent as a message to the child and adolescent psychiatrists in Turkey. One hundred sixty-one physicians working in the field of child and adolescent psychiatry participated in the study. Aripiprazole (32.2%), risperidone (30.4%), and quetiapine (14.9%) were three most commonly prescribed antipsychotics. Disruptive behavior-related disorders (28.9%), behavior problems related to autism spectrum disorder (20.7%), behavior problems related to intellectual disability (14.5%), and attention-deficit/hyperactivity disorder (12.4%) were the most common diagnoses requiring antipsychotics medications. Before starting antipsychotic treatment, the most commonly evaluated parameters were body mass index (BMI) (47.2%), waist circumference (10.5%), blood pressure (28.5%), lipid profile (37%), and blood glucose level (41.6%). When the evaluations made at least in a year after starting antipsychotic drug therapy were examined, 80.2% of physicians reported blood glucose, 79.6% lipid profile, 65.7% BMI, 59.1% blood pressure, and 26.6% waist circumference measurement almost always done. The results showed that the adherence to recommendations in guidelines for the screening of antipsychotic-related side effects was low. This study suggests that interventions should be made about antipsychotic monitoring training to physicians.

摘要

这项研究的目的是评估儿童精神科医生开的抗精神病药物以及他们对这些药物的后续治疗。这项研究的范围包括在该领域工作的顾问医师和儿童精神科住院医师。我们创建了一份问卷,评估医生使用抗精神病药物和后续治疗过程。该调查涉及 19 个问题。调查内容包括人口统计学数据、抗精神病药物的短期和长期随访、副作用干预策略以及最常开的抗精神病药物的诊断。该调查通过电子邮件发送,并以消息的形式发送给土耳其的儿童和青少年精神科医生。有 161 名在儿童和青少年精神科领域工作的医生参与了这项研究。阿立哌唑(32.2%)、利培酮(30.4%)和喹硫平(14.9%)是最常开的三种抗精神病药物。需要抗精神病药物治疗的最常见诊断包括与破坏性行为障碍相关的疾病(28.9%)、与自闭症谱系障碍相关的行为问题(20.7%)、与智力障碍相关的行为问题(14.5%)和注意力缺陷/多动障碍(12.4%)。在开始抗精神病药物治疗之前,最常评估的参数是体重指数(BMI)(47.2%)、腰围(10.5%)、血压(28.5%)、血脂谱(37%)和血糖水平(41.6%)。当检查开始抗精神病药物治疗至少一年后的评估结果时,80.2%的医生报告几乎总是测量血糖,79.6%测量血脂谱,65.7%测量 BMI,59.1%测量血压,26.6%测量腰围。结果表明,遵循抗精神病药物相关副作用筛查指南的建议的依从性较低。这项研究表明,应该对医生进行抗精神病药物监测培训方面的干预。

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