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Zippering Up a Role for ZO-1 in Atrioventricular Node Conduction and Disease.

作者信息

Liang Yan, Sheikh Farah

机构信息

From the Department of Medicine, University of California San Diego, La Jolla.

出版信息

Circ Res. 2020 Jul 3;127(2):298-300. doi: 10.1161/CIRCRESAHA.120.317291. Epub 2020 Jul 2.

DOI:10.1161/CIRCRESAHA.120.317291
PMID:32614716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8204722/
Abstract
摘要

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本文引用的文献

1
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.ZO-1 调节闰盘组成和房室结传导。
Circ Res. 2020 Jul 3;127(2):e28-e43. doi: 10.1161/CIRCRESAHA.119.316415. Epub 2020 Apr 29.
2
Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function.心肌细胞中 ZO-1 的表达对于正常房室传导是必需的，但不会改变心室功能。
Circ Res. 2020 Jul 3;127(2):284-297. doi: 10.1161/CIRCRESAHA.119.315539. Epub 2020 Apr 29.
3
Whole-Exome Sequencing Identifies Pathogenic Variants in TJP1 Gene Associated With Arrhythmogenic Cardiomyopathy.全外显子组测序鉴定出与心律失常性心肌病相关的 TJP1 基因的致病性变异。
Circ Genom Precis Med. 2018 Oct;11(10):e002123. doi: 10.1161/CIRCGEN.118.002123.
4
The Anatomy, Development, and Evolution of the Atrioventricular Conduction Axis.房室传导轴的解剖、发育与进化
J Cardiovasc Dev Dis. 2018 Aug 22;5(3):44. doi: 10.3390/jcdd5030044.
5
Cardiac Cx43, Cx40 and Cx45 co-assembling: involvement of connexins epitopes in formation of hemichannels and Gap junction channels.心脏中Cx43、Cx40和Cx45的共同组装：连接蛋白表位在半通道和缝隙连接通道形成中的作用。
BMC Cell Biol. 2017 Jan 17;18(Suppl 1):3. doi: 10.1186/s12860-016-0118-4.
6
Multilevel analyses of SCN5A mutations in arrhythmogenic right ventricular dysplasia/cardiomyopathy suggest non-canonical mechanisms for disease pathogenesis.致心律失常性右室发育不良/心肌病中SCN5A突变的多层次分析提示疾病发病机制的非典型机制。
Cardiovasc Res. 2017 Jan;113(1):102-111. doi: 10.1093/cvr/cvw234.
7
Tight junctions: from simple barriers to multifunctional molecular gates.紧密连接：从简单的屏障到多功能分子门控。
Nat Rev Mol Cell Biol. 2016 Sep;17(9):564-80. doi: 10.1038/nrm.2016.80. Epub 2016 Jun 29.
8
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.柯萨奇病毒和腺病毒受体（CAR）介导小鼠心脏中的房室结功能和连接蛋白45定位。
J Clin Invest. 2008 Aug;118(8):2758-70. doi: 10.1172/JCI34777.
9
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells.闭合小带蛋白-1的缺乏会导致胚胎致死表型，这与卵黄囊血管生成缺陷和胚胎细胞凋亡有关。
Mol Biol Cell. 2008 Jun;19(6):2465-75. doi: 10.1091/mbc.e07-12-1215. Epub 2008 Mar 19.
10
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions.紧密连接蛋白ZO-1与果蝇分隔连接中的盘大肿瘤抑制蛋白同源。
Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7834-8. doi: 10.1073/pnas.90.16.7834.