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提高对 2 型糖尿病缓解的理解:英国糖尿病协会 2019 年缓解研讨会的研究建议。

Improving understanding of type 2 diabetes remission: research recommendations from Diabetes UK's 2019 remission workshop.

机构信息

Diabetes UK, UK.

University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.

出版信息

Diabet Med. 2020 Nov;37(11):1944-1950. doi: 10.1111/dme.14358. Epub 2020 Jul 26.

DOI:10.1111/dme.14358
PMID:32614973
Abstract

AIM

To describe the process and outputs of a workshop convened to identify key priorities for future research in the area of remission of type 2 diabetes, and provide recommendations to researchers and research funders on how best to address them. With the ultimate aim of enabling the remission of type 2 diabetes to become a possibility for more people.

METHODS

A 1-day research workshop was conducted, bringing together 31 researchers, people living with diabetes, healthcare professionals and members of staff from Diabetes UK to identify and prioritize recommendations for future research into remission of type 2 diabetes.

RESULTS

Workshop attendees identified 10 key themes for further research. Four of these themes were prioritized for further focus: (i) understanding how to personalize lifestyle approaches based on biology, patient choice and subtypes; (ii) understanding the biology of remission; (iii) understanding the most effective approaches to implementation of lifestyle interventions; and (iv) understanding the best approaches to combining therapies (gut hormones, other drugs, lifestyle approaches and bariatric surgery).

CONCLUSIONS

This paper outlines recommendations to address the current gaps in knowledge related to remission of type 2 diabetes.

摘要

目的

描述为 2 型糖尿病缓解领域的未来研究确定关键优先事项而召开的研讨会的过程和成果,并就如何最好地解决这些问题向研究人员和研究资助者提供建议。最终目标是使更多人有可能实现 2 型糖尿病的缓解。

方法

举办了为期一天的研究研讨会,召集了 31 名研究人员、糖尿病患者、医疗保健专业人员以及英国糖尿病协会的工作人员,以确定和优先考虑进一步研究 2 型糖尿病缓解的建议。

结果

研讨会与会者确定了 10 个进一步研究的关键主题。其中 4 个主题被优先进一步关注:(i)了解如何根据生物学、患者选择和亚型个性化生活方式方法;(ii)了解缓解的生物学;(iii)了解实施生活方式干预的最有效方法;以及(iv)了解联合治疗(肠道激素、其他药物、生活方式方法和减重手术)的最佳方法。

结论

本文概述了为解决与 2 型糖尿病缓解相关的现有知识差距而提出的建议。

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