以淀粉酶引流液作为预测良性腮腺肿瘤术后涎瘘的指标。
Drain fluid amylase as a predictor of postoperative salivary fistula in cases with benign parotid tumours.
机构信息
Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhi-zao-ju Road, Shanghai, 200011, China.
Department of Oral and Maxillofacial Surgery (Zhang Zhiyuan Academician Workstation), Hainan Western Central Hospital (Shanghai Ninth People's Hospital, Hainan Branch), Danzhou, Hainan, 571700, China.
出版信息
BMC Oral Health. 2020 Jul 2;20(1):184. doi: 10.1186/s12903-020-01166-8.
BACKGROUND
Late diagnosis of a salivary fistula increases the risk of wound infection and scarring. The purpose of the present study was to identify a quantitative predictor of postoperative salivary fistula for cases treated with surgery.
METHODS
Demographic, intraoperative and postoperative parameters for 57 cases that received surgery for benign parotid tumours were recorded from June 2017 to June 2018, of which 18 cases developed salivary fistulas. These data were analysed using univariate and binary logistic regression analyses as well as receiver operating curve analysis.
RESULTS
Drain fluid amylase concentration was positively correlated with salivary fistula development (p < 0.001), with an odds ratio of 1.14 for a 1 KU/L increase in concentration and an optimal receiver operating curve cut-off value of 51,100 U/L for predicting salivary fistula development. Cases wherein the parotid-masseteric fascia remained intact were associated with a lower risk of salivary fistula development (p = 0.006).
CONCLUSION
Drain fluid amylase concentration may be a valuable predictor of postoperative salivary fistula in cases with benign parotid tumours.
背景
涎瘘的迟发诊断会增加伤口感染和瘢痕形成的风险。本研究旨在确定手术治疗后涎瘘的术后定量预测因子。
方法
回顾性分析 2017 年 6 月至 2018 年 6 月期间收治的 57 例腮腺良性肿瘤患者的临床资料，其中 18 例术后发生涎瘘。采用单因素和二项逻辑回归分析以及受试者工作特征曲线分析。
结果
引流液中淀粉酶浓度与涎瘘的发生呈正相关（p<0.001），浓度每增加 1KU/L，发生涎瘘的比值比为 1.14，预测涎瘘发生的最佳受试者工作特征曲线截断值为 51100U/L。腮腺咬肌筋膜保持完整的患者涎瘘发生风险较低（p=0.006）。
结论
对于腮腺良性肿瘤患者，引流液淀粉酶浓度可能是术后涎瘘的一个有价值的预测因子。
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