A brief history of FASEB and its programs and activities.

The Federation of American Societies for Experimental Biology (FASEB) was formed in 1912 to serve the needs of its four charter societies. Its growth, from these organizations with a little more than 300 members to nearly 30 societies with over 100 000 members, is a tribute to its ability to respond to the changing structure and needs of the experimental biology community. The Federation began as a loosely constructed, single-purpose organization established to facilitate the coordination of the annual meeting of its four member societies. Following World War II, the limitations of this informal structure became readily apparent, and the development of a professional staff under the leadership of Milton O. Lee ushered in the second phase of FASEB's history. Lee oversaw a period of substantial institutional growth, but when he retired in the mid-1960s the unresolved issues of governance and member autonomy loomed large. These became increasingly divisive sources of organizational friction and were not meaningfully resolved until the Williamsburg Retreat of 1989 restructured the Federation and initiated the third phase of its existence. The changes made as a result of this pivotal event gave FASEB a new (public affairs) and made the organization attractive to many other biomedical research societies. Membership grew rapidly in the 1990s and early years of the 21st century. This larger membership, along with changing financial relationships, present new challenges for the Federation and are precipitating another restructuring.