Research Institute of Diagnostic Radiology, Shin-Yurigaoka General Hospital, 255 Furusawa-tsuko Asaoku, Kawasaki, Kanagawa, 215-0026, Japan.
Department of Neurosurgery, Moriyama Neurological Center Hospital, Tokyo, Japan.
Acta Neurochir (Wien). 2020 Oct;162(10):2513-2517. doi: 10.1007/s00701-020-04468-6. Epub 2020 Jul 2.
We report the case of a patient with hypothalamic hamartoma (HH) who was successfully treated with magnetic resonance-guided focused ultrasound (MRgFUS) for ablation as a disconnection surgery. A 26-year-old man with gelastic epilepsy had been diagnosed with HH at 3 years of age, and antiepileptic drugs were administered due to worsening episodes. Magnetic resonance imaging showed a sessile parahypothalamic hamartoma and MRgFUS ablation was performed, creating an oval-shaped lesion at the boundary area of the HH. Dramatic improvements in seizure symptoms were noted, and he was seizure-free on decreased antiepileptic drugs without any adverse events over the 1-year follow-up period.
我们报告了一例下丘脑错构瘤（HH）患者的病例，该患者成功接受了磁共振引导聚焦超声（MRgFUS）消融治疗，作为一种离断手术。一名 26 岁的男性患者患有发笑性癫痫，3 岁时被诊断为 HH，由于发作加重，给予了抗癫痫药物治疗。磁共振成像显示一个位于下丘脑旁的无蒂错构瘤，进行了 MRgFUS 消融，在 HH 的边界区域形成了一个椭圆形的病变。在 1 年的随访期间，癫痫症状显著改善，在减少抗癫痫药物的情况下无癫痫发作，且无任何不良事件。
