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实时评估多发性硬化症患者中的 COVID-19 流行情况:一项多中心的欧洲研究。

Real-time assessment of COVID-19 prevalence among multiple sclerosis patients: a multicenter European study.

机构信息

Institute of Experimental Neurology, IRCCS Ospedale San Raffaele, via Olgettina 60, 20132, Milan, Italy.

Neurorehabilitation Unit, IRCCS Ospedale San Raffaele, Milan, Italy.

出版信息

Neurol Sci. 2020 Jul;41(7):1647-1650. doi: 10.1007/s10072-020-04519-x. Epub 2020 Jul 2.

Abstract

We assessed the prevalence and impact of COVID-19 among multiple sclerosis (MS) patients across Europe by leveraging participant data collected as part of the ongoing EU IMI2 RADAR-CNS major programme aimed at finding new ways of monitoring neurological disorders using wearable devices and smartphone technology. In the present study, 399 patients of RADAR-MS have been included (mean age 43.9 years, 60.7% females) with 87/399 patients (21.8%) reporting major symptoms suggestive of COVID-19. A trend for an increased risk of COVID-19 symptoms under alemtuzumab and cladribine treatments in comparison to injectables was observed. Remote monitoring technologies may support health authorities in monitoring and containing the ongoing pandemic.

摘要

我们利用正在进行的欧盟 IMI2 RADAR-CNS 主要计划中收集的参与者数据,评估了 COVID-19 在欧洲多发性硬化症(MS)患者中的流行程度和影响,该计划旨在寻找使用可穿戴设备和智能手机技术监测神经疾病的新方法。在本研究中,纳入了 399 名 RADAR-MS 患者(平均年龄 43.9 岁,60.7%为女性),其中 87/399 名患者(21.8%)报告了主要症状提示 COVID-19。与注射剂相比,观察到在使用阿仑单抗和克拉屈滨治疗时 COVID-19 症状的风险增加。远程监测技术可能支持卫生当局监测和控制正在进行的大流行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ba/7331489/37ca3506811a/10072_2020_4519_Fig1_HTML.jpg

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