Vegas V G, Beobide G, Castillo O, Reyes E, Gómez-García C J, Zamora F, Amo-Ochoa P
Department of Inorganic Chemistry, Autonomous University of Madrid, E-28049 Madrid, Spain.
Department of Inorganic Chemistry, University of the Basque Country (UPV/EHU), P.O. Box 644, E-48080, Bilbao, Spain and BC Materials, UPV/EHU Science Park, Barrio Sarriena s/n, E-48940 Leioa, Spain.
Nanoscale. 2020 Jul 16;12(27):14699-14707. doi: 10.1039/d0nr04166a.
The direct reaction between Cu(CH3COO)2 and uracil-1-acetic acid in water gives rise to the formation of a hydrogel consisting of entangled nanometric ribbons of a crystalline antiferromagnetic 1D Cu(ii) coordination polymer (CP) decorated with biocompatible uracil nucleobases. This hydrogel is the precursor for the preparation of a meso/macroporous ultralight aerogel that shows a remarkable Young's modulus. As a proof-of-concept of the molecular recognition capability of the terminal uracil moieties anchored at Cu(ii) CP chains, this material has been tested as the selective stationary phase for the separation of nucleobase derivatives in HPLC columns.
醋酸铜（Cu(CH3COO)2）与尿嘧啶-1-乙酸在水中直接反应，形成了一种水凝胶，该水凝胶由缠结的纳米级带状物组成，这些带状物是一种晶体反铁磁一维铜（II）配位聚合物（CP），上面装饰着生物相容性的尿嘧啶核碱基。这种水凝胶是制备具有显著杨氏模量的介观/大孔超轻气凝胶的前体。作为锚定在铜（II）CP链上的末端尿嘧啶部分分子识别能力的概念验证，这种材料已被测试用作高效液相色谱（HPLC）柱中分离核碱基衍生物的选择性固定相。
