Thomaidis T, Anastassea-Vlachou K, Mandalenaki-Lambrou C, Theodoridis C, Vrahnou E
Arch Dis Child. 1977 May;52(5):403-7. doi: 10.1136/adc.52.5.403.
Serum antitoxoplasma titres were determined simultaneously by the direct agglutination and the indirect immunofluorescent tests in 52 children aged 2 to 16 years having chronic lymph node enlargement, mainly cervical. Direct agglutination titres were raised (64 to 4096) in 22 children (42%), but rarely in the control groups of children with acute suppurative lymphadenitis, and healthy children, adults, nurses, and physicians. It is concluded that toxoplasmosis is commoner in Greek children than previously believed, and that it should be included in the differential diagnosis of lymphoglandular enlargement. Clinically the condition is mild and may be self-limited, but it should be treated promptly with trimethoprim-sulphamethoxazole, in order to prevent reactivation in adult life.
对52名年龄在2至16岁、主要表现为颈部慢性淋巴结肿大的儿童，同时采用直接凝集试验和间接免疫荧光试验测定血清抗弓形虫滴度。22名儿童（42%）的直接凝集试验滴度升高（64至4096），但在急性化脓性淋巴结炎儿童对照组、健康儿童、成人、护士和医生中很少出现这种情况。得出的结论是，弓形虫病在希腊儿童中比以前认为的更为常见，并且应将其纳入淋巴结肿大的鉴别诊断中。临床上这种情况较为轻微，可能是自限性的，但应立即用甲氧苄啶 - 磺胺甲恶唑进行治疗，以防止在成年后复发。
